176955
博碩士論文
Wen-Fu Lin, 林文福
碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 104 / Progranulins (PGRN) is a multifunctional growth factor that regulate cell proliferation, cell survival, tumorigenesis, inflammation, embryonic development, and tissue repair. When organisms are injured or infected, PGRN can be digested into granulin units (GRN) by elastases. GRN units have the function of innate immunity regulation. We had isolated several types of tilapia PGRN genes, PGRN1 and PGRN2, which encode 206 and 199 amino acids composed of two GRN units, ...