Zhi -Yu Chen, 陳緻宇

碩士 / 國立宜蘭大學 / 生物技術與動物科學系生物技術碩士班 / 101 / Groupers are considered to be the most important fish species of aquaculture with high economic value in Taiwan. But the most severe impact in groupers rasing course is significant mortality resulted from Iridovirus and leaded to groupers in low survival state. Now how to improve immunity of groupers to anti-viral infection is an urgent issue. This thesis mainly focused on the antibodies production and genes expression of GIV (grouper iridovirus)ORF059L, O...

CHEN,KUAN-CHOU, 陳冠州

碩士 / 國立高雄海洋科技大學 / 漁業生產與管理研究所 / 101 / To investigate and compare the relationships between biological and environmental factors among seven regions of artificial reefs in waters off Penghu County, two scientific echo sounders, a side scanning sonar, an ADCP and a bottom trawl were used to conduct the field surveys from June to November in 2012. Except the above comparisons, demersal organisms sampling and investigating surveys were carried out by scuba diving. Results showed that substrata in art...

Hong-Chung Chen, 陳鴻鈞

碩士 / 國立高雄海洋科技大學 / 水產食品科學研究所 / 101 / In this study, the functional properties and bioactive activity of defatted roe protein (RP) and roe protein hydrolysated (RH) were investigated. The functional properties of RP were studies including water absorption capacity, fat absorption capacity, emulsification ability, foaming ability, solubility, buffering capacity and moisture sprption isotherm. The protein and peptide contents of RH were determined. The sodium dodecyl sulfate polyacrylamide gel elect...

Yu-YouChen, 陳俞佑

碩士 / 國立成功大學 / 土木工程學系碩博士班 / 101 / The geological storage of CO2 is a technique to reduce greenhouse gas emissions. To estimate the storage pressure of a CO2 geological storage site, we must evaluate the in-situ stresses of reservoir rock. Acoustic Emission (AE) and Deformation Rate Analysis (DRA) are new core-based techniques to measure the pre-stress of the rock. However, the applicability of AE and DRA on the pre-stress evaluations is different from rock to rock and must be checked. In addition...

黃任佑

碩士 / 國立嘉義大學 / 水生生物科學系研究所 / 101

Yun-Chen Chang, 張芸甄

碩士 / 國立臺灣大學 / 海洋研究所 / 101 / Nitrogen and carbon stable isotopes were used to study the trophic dynamics of the billfishes and prey species in the waters off eastern Taiwan, and of the blue marlin in the Palau waters. White muscle samples were taken and frozen instantly at the Shinkang fish market of eastern Taiwan for the blue marlin, swordfish, black marlin and striped marlin captured in eastern Taiwan waters and the blue marlin captured in Paulau waters. Significant difference in δ15N was foun...

Jhih-Cyun Pan, 潘智群

碩士 / 國立彰化師範大學 / 生物技術研究所 / 101 / Thioacetamide (TAA) is one of the hepatotoxin that can cause liver fibrosis, cirrhosis and hepatocarcinoma, but the mechanism was still unclear. previous study, we have shown TAA can induce hydrogen peroxide, but not superoxide production. The oxidative stress markers include lipid peroxidation and protein carbonylation were higher in TAA treated group than control. In this study, histopathological alterations include liver cell diffuse and fatty infiltration were...

Tseng,Tzu-Yuan, 曾梓淵

碩士 / 國立高雄海洋科技大學 / 水產養殖研究所 / 102 / Currently, Streptococcus iniae (S. iniae) has become global aquaculture pathogen. The pathogen will infect fish and cause serious death and economy cost. This is a big threat to aquaculture. Those infected fish would have following symptoms: erratic swimming, darkening of the skin, exphthalmia, cornel opacity, ascites, peritonitiss, enlargement of spleen, petchiae around the anus etc. This study is mainly for prepare Streptococcus iniae killed bacterial vaccine...

Tsai, wen-jung, 蔡文榮

碩士 / 國立高雄海洋科技大學 / 水產食品科學研究所 / 101 / To elucidate the hygienic quality of commercial pacific saury, 39 samples collected from the supermarket (16 samples), traditional market (17 samples) and fishery processing plant (6 samples) were tested to determine chemical and microbial quality, and biogenic amine contents. The levels of salt content, ash content, water content, water activity, pH, total volatile basic nitrogen (TVBN), aerobic plate count (APC) and coliform in commercial pacific saury sampl...

Shiuan-Shian Lin, 林瑄賢

碩士 / 國立高雄海洋科技大學 / 水產食品科學研究所 / 102 / The research of this study was designed to investigate the feasibility of partially replacing the fish meal in feeds with using Lactobucillus acidophilus fermented corn gluten. In animal experiments, giant seaperch (Lates Calcarifer) were randomly allocated into control and three experimental groups with 15 %, 30 % and 45 % replacement (name FCG15, FCG30 and FCG45, respectively) for feed meal by fermented corn gluten ( containing 18% protein and 7% fat in all...

Yu Chen, 程予

碩士 / 國立臺灣大學 / 海洋研究所 / 101 /

Che-Hsien Su, 蘇哲賢

碩士 / 國立臺灣大學 / 漁業科學研究所 / 101 / Ca2+ is a vital element that serves various physiological roles in vertebrates. In vertebrates which include fish, Ca2+ homeostasis is an important issue. Freshwater fish normally face fluctuating Ca2+ conditions, and therefore it is critical for fish to control Ca2+ flow (into or out) of their bodies. Parathyroid hormone has been well documented to be a vital endocrine regulating Ca2+ uptake in mammals, however, remains largely unclear in teleosts. In present study...

Wei-Ting Chen, 陳維婷

碩士 / 中國醫藥大學 / 營養學系碩士班 / 101 / Acetaminophen (APAP), a commonly used antipyretic and analgesic agent, could cause acute liver injury by overdose. Houttuynia cordata Thunb is a medicinal plant used in traditional Chinese medicine. The aim of this study was to examine the hepatoprotective effects of Houttuynia cordata Thunb aqueous extract (HCE) against APAP-induced injury. Male C57BL/6JNarL mice were randomly divided into normal group, control group and HCE group. After 5 weeks supplementation, mi...

Yu-chieh Hsu, 徐于絜

碩士 / 中國醫藥大學 / 生物科技學系碩士班 / 99 / Deguelin, is a natural product, isolated from Derris trifoliata Lour. It was reported that deguelin inhibited cell proliferation and caused cell death in human leukemia and breast cancer cells through the induction of apoptosis. Therefore, we investigate deguelin whether or not affect human lung cancer cells in vitro . First, we observed the change of cell morphology and percentage of cell viability after various doses of deguelin treatment, flow cytometric analysi...

Chia-Chen, 林佳蓁

碩士 / 中山醫學大學 / 營養學系碩士班 / 99 / Hyperglycemia induced abundant free radicals formation, results in increased oxidative stress. The metabolic disorders resulted from insulin resistance also leaded to dyslipidemia, and excessive glucose favors polyol pathway, and increases the generation of advanced glycation end-products (AGEs), which finally causes diabetes complications. The crucian carp complex formula extract includes Carassius auratus, Dioscorea opposite, Lycium barbarum, and Rehmannia glutinos...

Hsuan-Chih Lin, 林暄智

碩士 / 國立澎湖科技大學 / 食品科學研究所 / 102 / Proximate composition of skin cuts of farm spectacled caiman (Caiman crocodiles) were determined. The moisture, ash, protein and fat content of the different partial skin of spectacled caiman were 49.36-63.19%, 8.01-20.81%, 26.20-30.17% and 0.12-0.23% (%wet basis), respectively. The high ash content (8-20%) of the skin was relation to the crocodilian scute covered the skin. Acid-soluble collagen (ASC) and pepsin-soluble collagen (PSC) were extracted from the skin ...

Chia-Chi Chang, 張家綺

碩士 / 國立高雄餐旅大學 / 餐旅管理研究所 / 102 / Sun Moon Lake, located in Yuchih Township, Nantou County, and featured by high mountains and lakes, aboriginal culture as well as nature ecology, attracts more than six million visits each year. D resort hotel has been constructed since September 2012. Although the whole construction has been built, due to many problems, its service and facilities are still in the air. In order to make owner plan more successful and make the planning customer-oriented, the study c...

LAI, JIA-WEI, 賴佳緯

碩士 / 靜宜大學 / 中國文學系 / 102 / Popular historical romance novels, derived from historical, legendary, if present, drama ... and so on, finishing and re-written from architecture. Ming Dynasty novel, one of the most representative category, the content is more diverse. In terms of age story distinguish covered the nations, Three, Five ...... so different, also have descendants compete judge the merits between novels. But the so-called superiority or inferiority, is beingproposedbythecontemporary .desc...

Sheng-Yun Wen, 溫勝芸

碩士 / 大仁科技大學 / 食品科技研究所 / 102 / Twenty-eight milkfish surimi were collected from traditional market, tourism market, stores and internet shopping in Taiwan and tested to determine the hygienic quality. The results showed that the pH value, salt content, ash content, water content , water activity, total volatile basic nitrogen (TVBN), total plate count (APC), coliform and Escherichia coli (E. coli) in all samples were ranged from 5.23-6.07 , 0.90-1.58% , 1.79-2.96%, 0.96-0.98, 61.87-75.87%, 1.19-2...

Tsai-Wen Lung, 龍采彣

碩士 / 國立雲林科技大學 / 環境與安全衛生工程系 / 102 / This research aimed to find the relationship between the toxicity of Diethyl phthalate (DEP) and zebrafish(Danio rerio) physiological reactions at different life stages. The life Stages of zebrafish growth are embryo, larva, juvenile and adult respectively. First, DEP tolerant tests investigated the effects of DEP concentration in the zebrafish and decided the high, medium and low concentration. Second, these high, medium and low concentration as a follow-up us...

Jia-Hua Lin, 林佳樺

碩士 / 國立臺灣海洋大學 / 食品科學系 / 100 / The cell and zinc concentrations in head kidney and blood of common carp elevated under stress. It suggests that there might be a membrane protein receptor on the cell surface of the head kidney cells, and zinc might combine with the receptor and induce the proliferation of the head kidney cells. Common carp head kidney were extracted with detergent lubrol to extract the membrane protein . Zinc binding protein in the detergent extract were separated with Zn2+-IMAC ...

Yao-Cheng Lyu, 呂曜丞

碩士 / 國立臺灣海洋大學 / 食品科學系 / 100

王士豪

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / The objective of this study was to investigate the myo-inositol metabolism in hybrid tilapia (Oreochromis aureus(♀)×O.niloticus(♂)) with a modified cannulated urine collector through the observation on the 24-hour changes of plasma and urine concentration of myo-inositol at various sampling time points as well as the 24-hour amlumulation of metabolites myo-inositol in the muscle,liver and heart after initiation of exogenous input either by oral administration or ca...

Teng-Yuan Hsu, 許騰元

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / The aim of this study is to evaluate the effects of different pigment sources and levels on skin coloration of koi and gold fish. Experiment I: Goldfish(3.22g) and koi(26.87g) were fed with diets containing synthetic astaxanthin (5, 10, and 15 g/kg), Chlorella Powder (20, 40, and 60 g/kg), Rose Pink (20, 40, and 60 g/kg) and control (without carotenoid) for 30 days, respectively. Skin coloration and weight were measured individually at the end of the experiment. Co...

Wai-Sang Ip, 葉偉生

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / Abstract The present study was designed to investigate the physical properties and immune effects of oral vaccines using encapsulated Vibrio alginolyticus or Vibrio carchariae as sodium alginate microparticles in vaccinated groupers and also to study the immune response of grouper after vaccination with both oil and aluminum adjuvanted bivalent vaccine of Vibrio alginolyticus and Vibrio carchariae delivered via intraperitoneal injection. In the preparation of micr...

Chia-Jung Kuo, 郭家榮

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / Three experiments investigated the effects of different pigment levels on the growth performance and skin pigmentation of angelfish, Pterophyllum scalare. Diet contained Spirulina (2%、4%、6%), rose pink (2%、4%、6%), and synthetic astaxanthin (0.05%、0.1%、0.2%) were fed 4.16±0.06g angelfish in the first experiment. Duration of experiment was six weeks. Angelfish fed diet containing 0.2% synthetic astaxanthin had significant higher weight gain than those fed other grou...

Shin-Han Wu, 吳欣翰

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / This study investigated the immunological protection by applying injectable and oral vaccines of Vibrio parahaemolyticus strain VHG, and yolk IgY pre-immunized with the same vaccines against the bacterial injection in juvenile grouper. The bacterium originally isolated from diseased groupers was used in this study for experimental purposes including vaccine preparation and virulence test. The LD50 value of the bacterium in grouper was 2.33x105 CFU/g fish body weigh...

Yi-Yang Chen, 陳義洋

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / The genus Corydoras is the most speciose of Siluriformes, and includes more than 150 species. The reference records about osteology of Corydoras are few. Therefore, this dissertation applies the clearing and staining methods to probe into early skeletal development in larvae and juvenile of Corydoras aeneus, C. paleatus, and C. sterbai. However, the clearing and staining methods are used separately. The anus and mouth evolve, also we observe the anterior ceratohyal...

Tzer-Yow Kuo, 郭則佑

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / The investigated the protective effects of active and passive immunization using the vaccines of Vibrio vulnificusGPB2 strainand the yolk immunoglobulin (IgY) from hens pre-immunized with the bacterium in the grouper(Epinepheluscoioides)juveniles.The bacterium was isolated from the blood of diseased grouper with ulcers and hemorrhaging on body surface and the LD50 value for fish was 1x105 CFU/g fish body weight. In the active immunization trials, the best protect...

Chih-Hao Tang, 湯之皓

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 100 / Previously, we cloned and characterized the zebrafish agr2 gene. Whole-mount in situ hybridization demonstrated that zebrafish agr2 is expressed in most organs that contain mucus-secreting cells, including epidermis, olfactory bulbs, otic vesicles, pharynx, esophagus, pneumatic duct, swim bladder, and intestine. However, detailed regulatory mechanisms regarding agr2 expression in specific organ such as otic vesicles are lacking. In this study, by serial deletion, ...

Tzu-Yung Lin, 林子詠

博士 / 國立臺灣海洋大學 / 食品科學系 / 100 / Summary Zinc is an essential nutrient for most organisms. The content of zinc in most tissues of different species is on the order of 10 ~ 100 μg/g wet weight. However, the common carp Cyprinus carpio has high zinc contents in its digestive tract tissue (562 ± 287 μg/g fresh tissue) which is not seen in other fishes. The common carp is able to survive days of anoxia at room temperature and can survive for several months at temperatures between 4 ~ 35℃. In this r...

Chih-Chi Chen, 陳智琦

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 100 / There are two Akirin genes, Akirin1 and Akirin2, in vertebrates. Akirin1 is a nuclear factor negatively regulated by myostatin and has been shown to be a promyogenic factor in skeletal myogenesis. Akirin1 can regulate the basic helix-loop-helix myogenic regulator factor (MRF) family, MyoD and Myogenin. Drosophila Akirin and mouse Akirin2 are highly conserved nuclear proteins required for NF-kappaB-dependent innate immune responsive gene expression. In zebrafish, Ak...

Shiou-wen Chiou, 邱秀雯

碩士 / 大仁科技大學 / 食品科技研究所 / 100 / Abstract To probe into hygienic quality and risk of histamine poisoning of salted mackerel products selling in markets, this research collected 35 salted mackerel products from traditional markets and supermarkets in seven areas in Taiwan, carried out investigation on hygienic quality, biogenic amines contents, and isolation of histamine-producing bacteria. Outcomes of research showed that contents of pH, salinity, water activity, Total volatile basic nitrogen, Aero...

Chia-che Shen, 沈佳哲

碩士 / 國立雲林科技大學 / 環境與安全衛生工程系碩士班 / 100 / The study was mainly concerned with the toxic effects of the DBP on zebrafish three developmental stages (embryo, larvae and adult fish). The results show that zebrafish embryo under different exposure time of 24, 48, 72 and 96 hours result in the different LC50(median lethal concentration) value at 2.5 mg/L, 1.1 mg/L 0.8 mg/L and 0.5 mg/L respectively. Adult zebrafish LC50-96hours is 8.68 mg/L. Larvae LC50-12hours is 3.33 mg/L. Showing zebrafish DBP tolera...

Yu-Ching Chang, 張育菁

碩士 / 國立雲林科技大學 / 文化資產維護系碩士班 / 100 / A procedure is Taiwan''s industrial cultural heritages over the past were designated as historic buildings and monuments by a single building, the Cultural Heritage Preservation Law added "cultural landscape" of the project in 2005, the concept of protected areas as a whole, however, how to define the industrial cultural heritage? Therefore, this study will be modified by Yuchih Branch, Tea Research and Extension Station as research object, through th...

Yun-Chich Ku, 古雲傑

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 101 / Global warming is one of the most serious problem recently . It caused fishing and aquaculture to be influenced . reducing greenhouse gas is the best measures to debase greenhouse gases immediately . In order to find out the greenhouse gases emission of aquaculture that have this investigation for greenhouse gases . According to the result , analyze for reduce discussion for this purpose carbon labels to receives authenticate which can promote products and appearan...

Jia-He Wang, 王佳禾

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 101 / Tbx5 is a member of the T-box transcription factor family which expresses in the heart for limbs/pectoral fin and eyes of vertebrate animals during embryonic development. In zebrafish embryos, using the specific antisense oligonucleotide to inhibit the tbx5 gene expression, the cartilage condensation of pectoral fin ceases. The DNA microarray revealed the expression of cartilage development related genes declined in tbx5 gene knockdown embryos, further analyzed and...

Wei-Siang Chen, 陳薇向

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 101 / Viral infections have been increasingly reported in cultured marine fish. Among these infections, viral encephalopathy and retinopathy (VER), caused by betanodaviruses (piscine nodavirus), is one of the most devastating, occurring in a variety of marine fish all over the world. Histological examination of tissues from the central nervous system and the retina often reveals areas of conspicuous tissue vacuolation and necrosis. Their genome consists of two molecules ...

Yi-Hsuan Lin, 林宜璇

碩士 / 國立臺灣海洋大學 / 食品科學系 / 101 / Monacanthidae is a trawl catch and common species in the market of Northeast and Southwestern areas of Taiwan. The objectives of this study are to investigate biochemical characteristics, amino acid constituents and antioxidant activities of collagen from Aluterus monoceros and Thamnaconus modestus skin. The crude protein contents of Aluterus monoceros and Thamnaconus modestus skin were 20.31 and 14.86%, and crude fat were 0.17 and 0.22%, respectively. The yields of...

Jen-Kuei Chiu, 邱仁奎

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 100 / Free radicals are formed with an atom or molecule containing unpaired electron. The most abundant free radical species is reactive oxygen species (ROS) that are produced during anaerobic metabolism. The free radical theory of development hypothesizes that an adequate ROS production make cell toward differentiation, but excess ROS production threatens cell surviving. Here I have examined the ROS accumulation and mitochondria biogenesis in zebrafish embryos by CM-H2...

Kuan-Te Chen, 陳寬德

碩士 / 國立臺灣海洋大學 / 海洋生物研究所 / 100 / The genus Fusigobius whitely, 1930 is a group of small marine benthic gobies. There are 11 valid species in the World so far. This research focus on all available Fusigobius species collected from Taiwan. There are 6 valid species species including an undescribed species and a newly recorded species: Fusigobius melacron. The molecular phylogenetic approach has been conducted by 4 fragments of partial sequences of mtDNA ND5 (about 990 bp), Cyt B (801 bp), COI (...

Lin, Wen-Wei, 林文惟

碩士 / 國立中正大學 / 戰略暨國際事務研究所 / 102 / Globalization has become an inevitable trend in the 21st century. As traffic and Internet’s rapid development shorter the distance between countries, the frequency countries interaction increases. The international community comes into an alliance with each other and compete on other stage, becoming a global risk. On the other word, when a country threatens, other countries will be affected, and any country are not isolated from the outside in close interaction w...

Chien, Yu-Chen, 簡毓蓁

碩士 / 國立臺灣藝術大學 / 表演藝術教學碩士學位班 / 102 / From the implemented Grade 1-9 Curriculum to 12-Year Compulsory Education, the Ministry of Education has incorporated art education and athletics education into key educational policies. In response to the implementation of 12-Year Compulsory Education and the vigorous and diverse reading promotion and drama education, the story volunteer troupes constituted by story volunteers are undergoing a thriving development. Nonetheless, it is considerably difficult fo...

Chih-Ting Shih, 施繼庭

碩士 / 國立臺灣大學 / 生化科學研究所 / 100 / In eukaryotes, Four-and-a-half LIM domains (FHL) protein family is highly conserved. Structurally, the FHL proteins are composed of four closely connected LIM domains arranged in tandem, which are cysteine-rich double zinc finger motifs; and an N-terminal half LIM domain, which has one zinc finger motif. The LIM domain is known for mediating protein-protein interaction. Based on its protein-protein interaction properties, FHL protein family can interact with many pr...

Yi-Hsien Chen, 陳易賢

碩士 / 國立臺灣大學 / 漁業科學研究所 / 100 / To know the effects on growth, and non-specific immune responses from dietary supplement of fruiting bodies of Cordyceps militaris and rice medium of Cordyceps militaris on black carps（Mylopharyngodon piceus). In the following experiment will be in two parts, first experiment, adding fruiting bodies of Cordyceps militaris as dietary supplement on a dose-dependent 0, 0.25, 0.5, 1 and 2% as weight as total feeds. Second experiment, dose-dependent effects of rice mediu...

Chin-Chia Tien, 田覲嘉

碩士 / 國立臺灣大學 / 法律學研究所 / 100 / Sharks are considered to be a marine living resource, and as a resource, it has suffered from over fishing and irresponsible fishing activities from human use. Such activities leading to stock diminish and fisheries collapse. In recent years, this situation has drawn concerns and a trend of conservation and management have arisen. Such a trend can be viewed in both international law levels and domestic regulations. The conservation and management of sharks in interna...

Yu-Yun Ding, 丁郁芸

碩士 / 國立臺灣大學 / 分子與細胞生物學研究所 / 100 / MicroRNA-1 (miR-1), a 22-nucleotide, endogenous non-coding RNA, is a muscle-specific miRNA significantly expressed in cardiac and skeletal muscle. However, the detailed molecular regulatory mechanism of miR-1 in the skeletal muscle is still unknown. Therefore, using both miRNA pull-down assay and microarray analysis, we screened putative mRNA targets of miR-1 from whole-cell extracts of zebrafish embryos at 48-hpf, and seryl-tRNA synthetase (sars) was obtained. ...

Moo-Rung Loo, 盧慕蓉

碩士 / 國立臺灣大學 / 分子與細胞生物學研究所 / 100 / microRNA-206 is a muscle-specific miRNA that regulate myoblast proliferation and differentiation. According to Labeled miRNA pull-down assay (LAMP), the candidate gene rtn was screened from 16-hpf zebrafish embryo which at the transition state between proliferation and differentiation of muscle cell. Through in vitro and in vivo system, we found out that miR-206 was able to repress reporter activity and up-regulated the expression of post-transcription level thr...

Chia-Jung Lin, 林嘉蓉

碩士 / 國立臺灣大學 / 生物環境系統工程學研究所 / 100 / The purpose of this thesis was to investigate the effects of pulsed waterborne Cu on the ecophysiological responses and the population dynamics of tilapia. This study reanalyzed the published acute and chronic toxicity and bioaccumulation data of tilapia and took into account the bioavailability for estimating the ecophysiological parameters of each life stage. This study used mechanistic models to estimate the vital rates for tilapia. Further, this study used ...

Wan-Ling Yao, 姚琬玲

碩士 / 國立臺灣大學 / 動物學研究所 / 100 / Hypoxia is known to regulate gene expression via hypoxia- inducible factors (HIFs) and plays a role in many developmental processes, including vasculogenesis, angiogenesis, heart and central nervous system development. The Hif1α knockout mice shows defective heart development, including cardia bifida and abnormal neural crest migration. Recently, we have observed heart left-right asymmetric defects and cardia bifida in zebrafish embryos deficient in lysophosphatidic ...