Che-yen Chiu, 邱哲彥

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 103 / Soft corals of the genus Lobophtum and Clavularia have been proved to yield a wide variety of bioactive secondary metabolites. In this study, research for secondary metabolites of soft corals Lobophytum solidum and Clavularia flava have led to the isolation of seven new compounds. Among these, four new cembranoids 1–3 and 5, along with two known compounds 4 and 6 were isolated from L. solidum collected at Dongsha Atoll. In addition, the acetone-solubles of C....

Fan,Tung-Yung, 樊同雲

博士 / 國立臺灣大學 / 海洋學系 / 84 / The sexual reproduction, life histories and population dynamics of four species of foliaceous corals, Echinopora lamellosa, Echinophyllia aspera, Mycedium elephantotus, and Merulina ampliata, in Yenliao Bay northern Taiwan and Nanwan Bay southern Taiwan were studied. The four coral species are hermaphroditic broadcast spawners. Colony size at sexual maturity was about 5-10 cm in d...

Lin,Ming-Chao, 林明炤

博士 / 國立臺灣大學 / 海洋學系 / 84 / Cology morphology and mechanical properties of sixteen sympatric alcyonaceans including six Sarcophyton, three Lobophytum, six Sinularia, and one Nephthea species were studied. Analyses of drag coefficient, flexibility, elastic modulus and breaking stress of alcyonacean colonies were conducted to demonstrate the relationships among colony morpholgy, deformation, stiffness and stre...

Kao, Hui-May, 高惠美

碩士 / 國立海洋大學 / 海洋生物研究所 / 84 /

Jui-Hsin Su, 蘇瑞欣

碩士 / 國立中山大學 / 海洋資源學系 / 87 / Continuing study on the chemical constituents of the gorgonian coral Briareum excavatum has led to the isolation of twelve new briarane-type diterpenoids 1-12. They are briaexcavatolides A-J (1, 4-12), Excavatolide L (3) and Excavatolide Z (2). The structures and relative stereochemistry of compounds 1-12 were elucidated by spectral and chemical methods and by comparison of their spectral and physical data with those of other structurally similar briarane diterpenes. ...

戴大欣

碩士 / 國立臺灣大學 / 地質學研究所 / 84 /

You, Zhi Kai, 游智凱

碩士 / 國立臺灣大學 / 海洋研究所 / 84 /

Meng-Lan Chang, 張夢蘭

碩士 / 國立屏東科技大學 / 森林系 / 93 / Viburnum odoratissimun (Caprifoliaceae) is an indigenous tree species to Taiwan. The species mainly distributes in the southern part of Taiwan. Flowers bloom between the late November to the early April. Fruit sets between the late January to the early August. Inflorescence is paniculate-cymose. Petal in corolla is arranged monosymmetry. The surface of bract and flower axis is cover with numerous trichomes. Initiation order of floral primordia is centripetal or acropet...

Hsiao-Wen Chiu, 邱筱雯

碩士 / 國立宜蘭大學 / 生物技術與動物科學系 / 103 / Six polysaccharides from marine organisms were evaluated for their immune modulation activities in murine macrophages. Polysaccharide from Pseudopterogorgia americana (PPA) was found to induce TNF-α and IL-6 secretion, and COX-2 expression in RAW 264.7 macrophages. PPA-mediated TNF-α and IL-6 secretion were partially through reactive oxygen species (ROS) associated pathways, as anti-oxidant N-acetyl-cysteine (NAC) reduced TNF-α and IL-6 secretion. PPA-mediated TN...

Tsung-chin Chang, 張宗勤

碩士 / 國立中山大學 / 海洋生物研究所 / 96 / The sexual reproduction of four gorgonian corals, Ellisella robusta, Subergorgia suberosa, Subergorgia mollis and Bebryce indica at Wanlitong, a non-upwelling area, and Talauko, an upwelling area, in south Taiwan were compared in order to understand their reproductive strategies. Four species were gonochoric. E. robusta, S. suberosa and S. mollis were broadcasting spawners with annual reproductive cycle. The reproductive mode of B. indica was not certain and it may r...

Kuan Hua, 林官嬅

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 101 / In order to discover bioactive compounds, we studied the chemical constituents from the organic extracts of the soft coral Sarcophyton tortuosum, collected from Orchid island. Separation of the ethyl acetate extract of the soft coral via repeated silica gel column chromatograph, followed by HPLC purification, yielded sixteen natural cembrane-type metabolites (1–16), including twelve new compounds, namely tortuolides A–C (1–3), sarcophytonol A (4), bistortuoli...

Shu-ting Liu, 劉書廷

碩士 / 國立中山大學 / 海洋生物研究所 / 99 / Many coral reefs around the world were damaged during the 1998 mass bleaching event. The acroporids in the lagoon of Dongsha Atoll were eliminated during massive bleaching, and they are still not recovered. Three hypotheses were proposed to explain how the lagoon of Dongsha Atoll has not recovered during the past twelve years：1. the lack of recruitment, 2. the persistent interfering on newly recruiting acroporids by hot water, 3.the interfering on those acroporids by...

Hwa-Pyng Chen, 陳華平

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 99 / Soft corals of the genus Lobophytum (Alcyoniidae) have been well recognized as a rich source of various secondary metabolites that have attracted much interest for the natural products chemists due to their structural complexity and remarkable pharmacological activities such as cytotoxicity, antibacterial activities, anti-inflammatory properties, and antiviral activity. Twelve cembrane diterpenes including six new secondary metabolites 1−6 were isolated organ...

Chen, Jian An, 陳建安

碩士 / 國立中山大學 / 海洋生物研究所 / 83 /

Chen, Zhi Yun, 陳智蘊

碩士 / 國立臺灣大學 / 地質研究所 / 82 /

Shih-tseng Lin, 林世增

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 98 / We have investigated the chemical constituents of the organic extracts of soft coral Lobophytum crassum, collected at Dongsha Atoll. This study has led to the isolation of eight new compounds, including six cembrane-type diterpenoids 1-6 and two a-tocopherol-type compounds 7 and 8 The chemical structures of compounds 1-8 were elucidated by extensive analysis of 1D, 2D NMR spectroscopic data (1H and 13C NMR、1H-1H COSY、HSQC、HMBC、NOESY), UV, IR, CD and MS. Compou...

Pei-wen Chen, 陳佩文

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 98 / Soft corals of the genus Sinularia have been proved to yield a wide variety of secondary metabolites. In order to search for novel bioactive substances from marine organisms, we have investigated the secondary metabolites of the soft corals Sinularia leptoclados and Sinularia sandensis. Chromatographic separation of the organic extracts of the Formosan soft coral Sinularia leptoclados, collected at Dongsha Atoll of the South China Sea, led to the isolation of ...

Hui-Ting Huang, 黃惠婷

碩士 / 嘉南藥理科技大學 / 藥物科技研究所 / 98 / The main purpose of this is to study the chemical constituents of the Formosan Isididae Isis hippuris and Original Plant Phyllanthus urinaria, as well as analyse their other analysis of biological activities. Ethyl acetate extracts of I. hippuris were found to show siginificant activity against SCC-25(human oral squamous cell carcinoma). Furthermore, Acetone extracts of P. urinaria were found to show moderate activity against Huh7 281 cell (human hepatocellular car...

Yu-Hsiang Chou, 周郁翔

碩士 / 國立臺灣大學 / 海洋研究所 / 90 / Sexual reproduction of three alcyonacean corals, Lobophytum pauciflorum, Sarcophyton crassocaule, and Sarcophyton trocheliophorum was studied in Nanwan Bay, southern Taiwan from March 2001 to April 2002. Three species are all gonochoric broadcasting spawners with gonads borne in the autozooids. The sex ratio (male : female) of L. pauciflorum and S. crassocaule is 46: 33 and 4: 3, respectively. However, only female was found in S. trocheliophorum. The smallest colony si...

Cheng, Mo Chi, 鄭模池

碩士 / 國立中山大學 / 海洋資源學系 / 84 /

HUANG, JIAN-JUN, 黃建軍

碩士 / 國立中山大學 / 海洋生物研究所 / 80 /

Chen, Yu-Xian, 陳育賢

碩士 / 國立臺灣大學 / 海洋研究所 / 71 /

ZHEN, KUANG-LONG, 鄭光龍

碩士 / 國立中山大學 / 海洋地質研究所 / 76 /

L.-F. Huang, 黃龍飛

碩士 / 國立中山大學 / 海洋資源學系研究所 / 90 / Abstract Several sesquiterpenes isolated from a Formosan gorgonian coral Isis hippuris have shown significant cytotoxic activity against various cancer cell lines. In order to search other active components, we have investigated the chemical constituent of I. hippuris from a Green Island specimen. In the cytotoxcity assay, the EtOAc extract showed potent cytotoxic response toward P-388, A549 and HT-29 cancer cell lines. Thus, the investigation on the chemical conte...

Ru-Ting Shiue, 薛如婷

碩士 / 國立中山大學 / 海洋資源學系研究所 / 90 / The chemical constituents of organic extracts of two Formosan soft corals Sinularia leptoclados and Sinularia nanolobata were studied. Investigation on S. leptoclados has led to the isolation of eight norditerpenes (1-8), including four new compounds, scabrolide A (1), leptolide A (2), leptolide B (3), leptolide C (4) and four know compounds (5-8), (11, 12)-epileptolide (5), ineleganolide (6), (1R*,5R*,8R*,10S*,11S*)—11—hydroxyl—1—isopropenyl—8—methyl—3,6—dioxo—5,8...

Yu-Chi Lin, 林玉麒

碩士 / 國立中山大學 / 海洋資源學系研究所 / 90 / ABSTRACT Soft corals have been proved to be a rich source of bioactive natural products. This research revealed isolation and structure elucidation of bioactive natural products in the Taiwanese soft coral Junceella juncea. The acetone extract of J. juncea collected in Ken-ting exhibited cytotoxicity against tumor cells. Bioassay- directed fractionation of the EtOAc-layer has resulted in the isolation of five new briaranes, designated juncenolides A-E (1-5) alon...

En-hung Lin, 林恩弘

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 95 / Five new diterpenes, GN67-12-5-4-2 (1)、GN67-12-6-4-2 (2)、GN67-20-4-3 (3)、GN67-25-6-1 (4)、GN67-12-5-12-1 (5) and four known terpenoides, GN67-12-5-12 (6)、GN67-28-5-3-3 (7)、GN67-28-5-4 (8)、GN67-23-4 (9) were isolated from the methylene chloride solubles of the Formosan soft coral Cespitularia hypotentaculata. Three new cytotoxic sesquiterpenes, GN78-14-3a-B (10)、GN78-22-8I-B (11)、GN78-17-3a-B (12) and five known terpenoides, GN78-12-5-B-G (13)、GN78-14-3a-N (14)、...

Yu-mine Su, 蘇毓閔

碩士 / 國立東華大學 / 海洋生物科技研究所 / 95 / In the continuing study on the chemical constituents of two gorgonian corals, Junceella fragilis and Ellisella robusta, collected off the coast of southern Taiwan, have resulted in the isolation of seven briarane-type natural products, including a new briarane, fragilide B (1), from J. fragilis and a new metabolite robustolide C (2) from the female E. robusta. In addition, a new chlorinated briarane, robustolide D (3), along with two known briaranes, umbraculolide ...

Mingjae Huang, 黃敏捷

碩士 / 國立中山大學 / 海洋資源學系研究所 / 92 / Chromotographic separations of Formosan soft coral Sarcophyton crassocaule (GN-55) led to the isolations of four diterpenes, sarcophine (1), sarcophytoxide (2), (7R*, 8S*)-dihydroxysarcophytonin A (3), sarcophtonin A (4), one steroid, 17��,20��-epoxy-23,24- dimethyl-cholest-5- ene-3��,22-diol (5), and an eudesmane sesquiterpene, selin-11- en-4��-ol (6). Two eudesmane epimers, 7 and 8 (new compound), three eudesmane sesquiterpenes, 9�{11, and a sphingolipid, 12 were...

ZHOU, YI-CHENG, 周一成

碩士 / 國立中山大學 / 海洋生物研究所 / 75 /

LIAO, ZHI-WEI, 廖至維

碩士 / 國立中山大學 / 海洋生物研究所 / 75 /

Chun-yu Lin, 林俊諭

碩士 / 國立海洋大學 / 海洋生物研究所 / 87 /

kuan-jen chen, 陳冠任

碩士 / 國立中山大學 / 海洋資源學系研究所 / 89 / Abstract Chromatographic separation of methylene chloride extract of Formosan stolonifer Tubipora musica Linnaeus (collected at Green Island) led to the isolation of nine sesquiterpenoids, GN32-17 (1), GN32-32 (2), GN32-66 (3), GN32-82 (4), GN32-83 (5), GN32-91 (6), GN32-94 (7), GN32-97 (8), and GN32-98 (9). Compounds 1, 2, 3, 6, 8, and 9 were new compounds . Compounds 4, 5, and 7 were known compounds. Compounds 1, 3, and 9 were new skeletons.

CHEN,ZHAO-LUN, 陳昭倫

碩士 / 國立中山大學 / 海洋生物研究所 / 78 /

QIU, ZONG-REN, 邱宗仁

碩士 / 國立海洋大學 / 海洋生物研究所 / 81 /

Hwang, Jia Peir, 黃家培

碩士 / 國立中山大學 / 海洋資源學系 / 81 /

CHEN, TIAN-YI, 陳天毅

碩士 / 國立中山大學 / 海洋生物研究所 / 81 /

Yong-Hsin Lu, 呂泳信

碩士 / 國立中興大學 / 生命科學院碩士在職專班 / 102 / Abstract Pleurotus is the white rot fungi and have ability to decompose wood. They are the major cultivation mushroom. There are about twelve varieties were cultivated in the world. The most cultivated in Taiwan are P. citrinopileatus, P. abalonus, P. ostreatus and P. eryngii. Among them, there is an increasing trend of Pleurotus citrinopileatus production, because of its short cultivated time, rich aroma, taste sweet and crisp, high nutrition value, and che...

王谷神

碩士 / 國立臺灣大學 / 地質科學研究所 / 91 /

Dai, Chang-Feng, 戴昌鳳

碩士 / 國立臺灣大學 / 海洋研究所 / 69 /

Guo, Ming Ren, 郭銘仁

碩士 / 國立臺灣大學 / 地質研究所 / 82 /

Shu, Zhao Rui, 舒兆瑞

碩士 / 國立臺灣大學 / 地質研究所 / 82 /

ZHANG, SHEN-MIN, 張聖明

碩士 / 國立臺灣大學 / 海洋研究所 / 80 /

Hsiu-Mei Yi, 易秀郿

碩士 / 中國文化大學 / 應用化學研究所 / 93 / The fresh stems of Euphorbia tirucalli L. were collected from Ping-Tung, Taiwan. It has been used as a folk medicine for treatment of the dermatosis, and pains of the human body paralysis. In earlier studies, the latex of E. tirucalli is known to be poisonous, and some phorbol esters isolated from E. tirucalli were shown to possess toxic tumor-promoting activity. However, recent reports showed that some of phorbol esters were very effective antiviral agents. Therefor...

CHEN, GUO-KUN, 陳國琨

碩士 / 國立臺灣大學 / 海洋研究所 / 73 /

Lin-Cyuan Huang, 黃琳權

碩士 / 國立東華大學 / 海洋生物研究所 / 107 / Study on the chemical constituents of the sea whip gorgonian Junceella fragilis had led to the isolation of five briarane-type diterpenoids, including two new briaranes, fragilides P (1) and Q (2), as well as three know analogues, juncin ZI (3), robustolide F (4), and juncin Z (5). In addition, six known eunicellins, litophynol B (6), scleropytin F methyl ether (7), klymollin W (8), cladiellisin (9), (1R*,2R*,3R*,6S*,7S*,9R*,10R*,14R*)-3-butanoyloxycladiell-11(17)-e...

Zhi-Jun Zhang, 張智鈞

碩士 / 國立東華大學 / 海洋生物研究所 / 107 / This study focused on the investigation of the chemical constituents of two octcorals identified as Paralemnalia thyrsoides and Cladiella sp., collected in the waters of Southern Taiwan. From the alcoholic extract of P. thyrsoides, two nor-sesquiterpenes, including a new natural product, (+)-pathylactone (1), and a known compound napalilactone (2), were isolated. The analysis of Cladiella sp. extract led to the isolation of 14 eunicellin-based diterpenoids, includin...

Hsiang-Lun Huang, 黃湘倫

碩士 / 國立中山大學 / 海洋科學系研究所 / 107 / Massive poritids often reached very large colony sizes in many Pacific reefs. A few hypotheses have been proposed and tested in this on-going study. I observed that the massive Porites spp indeed reached largest colony sizes at Dongsha Atoll; within habitats, however, the same is true only in seagrass beds, patch reefs and channels, but not in fore reefs. I mentioned two questions: (1) how come massive Porites could reach large sizes in seagrass beds while the othe...

Yu-hui Chen, 陳育輝

碩士 / 國立中山大學 / 海洋生物科技暨資源學系研究所 / 95 / This research focuses on diterpenoids from Taiwanese soft corals Xenia umbellata Lamarck, Junceella juncea Pallas and Junceella fragilis Ridley. Twelve diterpenoids in addition to one sesequiterpenoid were isolated. Our investigation of the soft coral X. umbellata Lamarck afforded five natural products, including two new xenicane diterpenes, xenibelatols A-B (1-2), together with two known xenicane diterpenes, 7,8-oxido- isoxeniolide (3), 9-hydroxyxeniolide-F (...

Wei-Ting Sun, 孫維廷

碩士 / 國立高雄海洋科技大學 / 水產養殖研究所 / 106