Lucia Capano, and Annie Dupuis, and Jessica Brian, and Deepali Mankad, and Lisa Genore, and Rianne Hastie Adams, and Sharon Smile, and Toni Lui, and Dina Odrobina, and Jane A. Foster, and Evdokia Anagnostou

Abstract Background Pioglitazone is a promising compound for treatment of core autism spectrum disorder (ASD) symptoms as it targets multiple relevant pathways, including immune system alterations. Objective This pilot study aimed to elucidate the maximum tolerated dose, safety, preliminary evidence of efficacy, and appropriate outcome measures in autistic children ages 5–12 years old. Methods We conducted a 16-week prospective cohort, single blind, single arm, 2-week placebo run-in, dose-findin...

Monica L. Schoch, and Judy Currey, and Liliana Orellana, and Paul N. Bennett, and Vicki Smith, and Alison M. Hutchinson

Abstract Background Point-of-care ultrasound (POCUS) has been used in various vascular access contexts; however, to date, it has not been widely adopted in haemodialysis clinics. People with end-stage kidney disease receiving haemodialysis require an arteriovenous fistula (AVF), arteriovenous graft (AVG), or central venous access device (CVAD) in order to access their blood for therapy/treatment. Cannulation issues, such as haematoma and extravasation, related to AVFs and AVGs are common. This p...

Frederick Ihunnaya O, and Enquobahrie Daniel, and Qiu Chunfang, and Abetew Dejene, and Williams Michelle A

<p>Abstract</p> <p>Background</p> <p>Insufficient sleep and poor sleep quality, considered endemic in modern society, are associated with obesity, impaired glucose tolerance and diabetes. Little, however, is known about the consequences of insufficient sleep and poor sleep quality during pregnancy on glucose tolerance and gestational diabetes.</p> <p>Methods</p> <p>A cohort of 1,290 women was interviewed during early pregnancy. We collected information about sleep duration and snoring during ear...

Tong WS, and Yuen AWT, and Wai CYY, and Leung NYH, and Chu KH, and Leung PSC

Wai Sze Tong,1,* Agatha WT Yuen,1,* Christine YY Wai,2 Nicki YH Leung,2 Ka Hou Chu,1 Patrick SC Leung3 1School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China; 2Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China; 3Division of Rheumatology, Allergy and Clinical Immunology, School of Medicine, University of California Davis, Davis, CA, USA *These authors contributed equally to this work Abstract: Seafood a...

Sanny M. Andrade-Porto, and Cleverson A. Ramos, and Rosemary Roque, and Elizabeth G. Affonso, and José F.M. Barcellos, and Marieta N. Queiroz, and Cleusa S.O. Araújo, and Marcos Tavares-Dias

ABSTRACT: This study aimed to determine the lethal concentration and the structural and ultra-structural effects caused by the formalin exposure on juveniles of Arapaima gigas. Ninety fish (60.1± 2.5g and 20.2±0.9cm) were exposed to 0, 22, 44, 66, 88 and 110mg L-1 in order to determine the lethal concentration (LC50-96h) that was 36.4mg L-1 of formalin. Sublethal effects were evaluated using histopathological analysis on the gills and assessment of behavioral alterations and clinical signs. The ...

Hale JF, and Terrien JM, and Quirk M, and Sullivan K, and Cahan M

Janet Fraser Hale,1 Jill M Terrien,1 Mark Quirk,2 Kate Sullivan,2 Mitchell Cahan3 1Graduate School of Nursing, University of Massachusetts Medical School, Worcester, MA, USA; 2Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA; 3Department of Surgery, University of Massachusetts Medical School, Worcester, MA, USA Purpose: Critical thinking underlies several Association of American Medical Colleges (AAMC)-defined core entrustable pro...

Takaomi Arai, and Razikin Amalina, and Zainudin Bachok

BACKGROUND: In order to understand feeding ecology and habitat use of coral reef fish, fatty acid composition was examined in five coral reef fishes, Thalassoma lunare, Lutjanus lutjanus, Abudefduf bengalensis, Scarus rivulatus and Scolopsis affinis collected in the Bidong Island of Malaysian South China Sea. RESULTS: Proportions of saturated fatty acids (SAFA) ranged 57.2% 74.2%, with the highest proportions in fatty acids, the second highest was monounsaturated fatty acids (MUFA) ranged from 2...

ALVARO MIQUEL, and ILSE MÜLLER, and PABLO FERRER, and PABLO D. T. VALENZUELA, and LUIS O BURZIO

We have used the expression library immunization technology to study the protection of Coho salmon Oncorhynchus kisutch to the infection with Piscirickettsia salmonis. Purified DNA from this bacterium was sonicated and the fragments were cloned in the expression vector pCMV-Bios. Two libraries were obtained containing 22,000 and 28,000 colonies and corresponding to approximately 8 and 10 times the genome of the pathogen, respectively. On average, the size of the inserts ranged between 300 and 1,...

RODRIGO GONZÁLEZ, and ARES TIRADO, and MONSERRAT BALANDA, and MIRIAM ALVO, and INÉS BARQUÍN, and PILAR DURRUTY, and SERGIO LOBOS, and DANIELA SEELENFREUND

Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases. Since insulin levels are misregulated in type 2 diabetes, a possible connection between DN and its decreased nephrin expression could be the presence of regulatory elements responsive to insulin in the nephrin gene (NPHS1) promoter region. In this work, using bioinformatic tools, we ...

Sen Ananda, and Wright Benjamin D, and Zick Suzanna M, and Arnedt J Todd

<p>Abstract</p> <p>Background</p> <p>Despite being the most commonly used herbal for sleep disorders, chamomile's (<it>Matricaria recutita</it>) efficacy and safety for treating chronic primary insomnia is unknown. We examined the preliminary efficacy and safety of chamomile for improving subjective sleep and daytime symptoms in patients with chronic insomnia.</p> <p>Methods</p> <p>We performed a randomized, double-blind, placebo-controlled pilot trial in 34 patients aged 18-65 years with DSM-IV...

Joshua Chou, and Jia Hao, and Shinji Kuroda, and Besim Ben-Nissan, and Bruce Milthopre, and Makoto Otsuka

The aim of this study was to examine the bone regeneration properties of beta-tricalcium phosphate hydrothermally converted from foraminifera carbonate exoskeleton in the repair of rat calvarial defect. These natural materials possess unique interconnected porous network with uniform pore size distribution, which can be potentially advantageous. In total, 20 adult male Wistar rats received full-thickness calvarial defect with a diameter of 5 mm. The rate of newly formed bone was measured radiolo...

H. Andersen, and H. Andersen, and J. Cermak, and J. Cermak, and J. Fuchs, and J. Fuchs, and R. Knutti, and U. Lohmann

The role of aerosols, clouds and their interactions with radiation remain among the largest unknowns in the climate system. Even though the processes involved are complex, aerosol–cloud interactions are often analyzed by means of bivariate relationships. In this study, 15 years (2001–2015) of monthly satellite-retrieved near-global aerosol products are combined with reanalysis data of various meteorological parameters to predict satellite-derived marine liquid-water cloud occurrence and pr...

Afriani Ramadhan, and Sri Nuryati, and Nur Bambang Priyoutomo, and Alimuddin Alimuddin

<p class="NoParagraphStyle"><strong>ABSTRACT</strong></p><p class="NoParagraphStyle"><em> </em></p><p class="NoParagraphStyle">This study was aimed to evaluate the dietary ambon lumut banana <em>Musa cavendishii</em> var. dwarf Paxton stem extract on the immune responses, growth, and survival rate of Pacific white shrimp against white spot disease. Ambon banana steam extract was obtained by maceration method using ethanol. The shrimps fed by pellet containing ambon banana stem extracts with diff...

Asuncion eMartinez, and Asuncion eMartinez, and Laure Anne eVentouras, and Laure Anne eVentouras, and Samuel T Wilson, and Samuel T Wilson, and David M Karl, and David M Karl, and Edward F DeLong, and Edward F DeLong

Aerobic degradation of methylphosphonate (MPn) by marine bacterioplankton has been hypothesized to contribute significantly to the ocean’s methane supersaturation, yet little is known about MPn utilization by marine microbes. To identify the microbial taxa and metabolic functions associated with MPn-driven methane production we performed parallel metagenomic, metatranscriptomic, and functional screening of microcosm perturbation experiments using surface water collected in North Pacific Subtropi...

Matthew J. Oliver, and Josh T. Kohut, and Kim Bernard, and William Fraser, and Peter Winsor, and Hank Statscewich, and Erick Fredj, and Megan Cimino, and Donna Patterson-Fraser, and Filipa Carvalho

Abstract Discovering the predictors of foraging locations can be challenging, and is often the critical missing piece for interpreting the ecological significance of observed movement patterns of predators. This is especially true in dynamic coastal marine systems, where planktonic food resources are diffuse and must be either physically or biologically concentrated to support upper trophic levels. In the Western Antarctic Peninsula, recent climate change has created new foraging sympatry betwee...

Jainee Lewis, and Esteban Soto

Abstract Background Francisella noatunensis subsp. orientalis (Fno) is an emergent fish pathogen and the etiologic agent of piscine francisellosis. Besides persisting in the environment in both biofilm and planktonic forms, Fno is known to infect and replicate inside tilapia macrophages and endothelial-derived cells. However, the mechanism used by this emergent bacterium for intracellular survival is unknown. Additionally, the basis of virulence for Fno is still poorly understood. Several potent...

Kay Vopel, and Cintya Del-Río, and Conrad A. Pilditch

Abstract Ocean acidification may alter the cycling of nitrogen in coastal sediment and so the sediment–seawater nitrogen flux, an important driver of pelagic productivity. To investigate how this perturbation affects the fluxes of NOX− (nitrite/nitrate), NH4+ and O2, we incubated estuarine sand and subtidal silt in recirculating seawater with a CO2-adjusted pH of 8.1 and 7.9. During a 41-day incubation, the seawater kept at pH 8.1 lost 97% of its NOX− content but the seawater kept at pH 7.9 lost...

Lida Xing, and Benjamin Sames, and Ryan C. McKellar, and Dangpeng Xi, and Ming Bai, and Xiaoqiao Wan

Abstract The mid-Cretaceous Burmese amber (~99 Ma, Myanmar), widely known for exquisite preservation of theropods, also yields microfossils, which can provide important contextual information on paleoenvironment and amber formation. We report the first Cretaceous ostracod in amber—the gigantic (12.9 mm) right valve of an exclusively marine group (Myodocopa: Myodocopida) preserved in Burmese amber. Ostracods are usually small (0.5–2 mm), with well-calcified carapaces that provide an excellent fos...

Cynthia Esmeralda Lizárraga-Velázquez, and Crisantema Hernández, and Gustavo Adolfo González-Aguilar, and José Basilio Heredia

Antioxidant capacities of hydrophilic (phenolic compounds; H-MPE) and lipophilic (carotenoids; L-MPE) antioxidants from mango peel by ABTS and DPPH assays were determined. The ability of H-MPE and L-MPE to inhibit fish oil peroxidation by the formation of malondialdehyde (MDA) was measured and compared against synthetic antioxidant butylated hydroxytoluene (BHT) to study their antioxidant potential in the stabilization of omega-3 polyunsaturated fatty acids contained in the fish oil. H-MPE and L...

Joshuva John, and He Liu

Glyphosate is the most widely used agricultural herbicide in the world and in the United States. In this study, we measured glyphosate levels in water, foods, and human urine samples. We also specifically examined possible correlations between urinary glyphosate levels and physiological, dietary, or behavioral factors. The results show that water samples obtained from both Lake Erie and tap water contained nondetectable or very low levels of glyphosate (≤0.08 ppb). On the other hand, food sample...

Athimed El Taher, and Nicolás Lichilín, and Walter Salzburger, and Astrid Böhne

Abstract Background Differential gene expression can be translated into differing phenotypic traits. Especially during embryogenesis, specific gene expression networks regulate the development of different body structures. Cichlid fishes, with their impressive phenotypic diversity and propensity to radiate, are an emerging model system in the genomics era. Here we set out to investigate gene expression throughout development in the well-studied cichlid fish Astatotilapia burtoni, native to Lake ...

Chen Huang, and Dongliang Leng, and Shixue Sun, and Xiaohua Douglas Zhang

Abstract Background Being critically important to the ecosystem, the stability of coral reefs is directly related to the marine and surrounding terrestrial environments. However, coral reefs are now undergoing massive and accelerating devastation due to bleaching. The fact that the breakdown of symbiosis between coral and the dinoflagellate, zooxanthellae, has been well elucidated as the main cause of bleaching, implying the establishment of symbiosis with zooxanthellae plays a crucial role in m...

Takeshi Hanyu, and Kenji Shimizu, and Takayuki Ushikubo, and Jun-Ichi Kimura, and Qing Chang, and Morihisa Hamada, and Motoo Ito, and Hikaru Iwamori, and Tsuyoshi Ishikawa

Volatile exchange between the Earth’s interior and surface layers is one of the central issues in mantle geochemistry. Here the authors present evidence that chlorine is transferred from the surface to the deep mantle by subducted oceanic crust, forming a chlorine-rich mantle reservoir.

Braband Anke, and Podsiadlowski Lars

<p>Abstract</p> <p>Background</p> <p>Mitochondrial genomes form units of genetic information replicating indepentently from nuclear genomes. Sequence data (most often from protein-coding genes) and other features (gene order, RNA secondary structure) of mitochondrial genomes are often used in phylogenetic studies of metazoan animals from population to phylum level. Pycnogonids are primarily marine arthropods, often considered closely related to chelicerates (spiders, scorpions and allies). Howev...

Hansson Anita, and Pålsson Gunvor, and Branell Ulla-Carin, and Ahrén Bo, and Granfeldt Yvonne, and Jönsson Tommy, and Söderström Margareta, and Lindeberg Staffan

<p>Abstract</p> <p>Background</p> <p>Our aim was to compare the effects of a Paleolithic ('Old Stone Age') diet and a diabetes diet as generally recommended on risk factors for cardiovascular disease in patients with type 2 diabetes not treated with insulin.</p> <p>Methods</p> <p>In a randomized cross-over study, 13 patients with type 2 diabetes, 3 women and 10 men, were instructed to eat a Paleolithic diet based on lean meat, fish, fruits, vegetables, root vegetables, eggs and nuts; and a Diabe...

Grubh Archis R., and Winemiller Kirk O.

The Western Ghats region of peninsular India contains high diversity of freshwater fishes that support artisanal fisheries, but no studies to date have investigated fish assemblages of the region's extensive wetlands. This study examined fish population densities and the structure of local species assemblages in pools of the Periyakulam wetland of the Western Ghats. From 2000 to 2001, fishes and local abiotic environmental parameters were surveyed during three periods with contrasting rainfall (...

Robertson D Ross, and Rocha Claudia R, and Rocha Luiz A, and Bowen Brian W

<p>Abstract</p> <p>Background</p> <p>Two processes may contribute to the formation of global centers of biodiversity: elevated local speciation rates (the center of origin hypothesis), and greater accumulation of species formed elsewhere (the center of accumulation hypothesis). The relative importance of these processes has long intrigued marine biogeographers but rarely has been tested.</p> <p>Results</p> <p>To examine how origin and accumulation affected the Greater Caribbean center of diversi...

Caut Stéphane, and Hulin Vincent, and Briane Jean-Paul, and Wongsopawiro Ronald, and Rivalan Philippe, and Girondot Marc, and Guirlet Elodie, and Godfrey Matthew H

<p>Abstract</p> <p>Background</p> <p>Marine turtles deposit their eggs on tropical or subtropical beaches during discrete nesting seasons that span several months. The number and distribution of nests laid during a nesting season provide vital information on various aspects of marine turtle ecology and conservation.</p> <p>Results</p> <p>In the case of leatherback sea turtles nesting in French Guiana, we developed a mathematical model to explore the phenology of their nesting season, derived fro...

Vilcinskas Andreas, and Altincicek Boran

<p>Abstract</p> <p>Background</p> <p>The marine annelid <it>Platynereis dumerilii </it>(Polychaeta, Nereididae) has been recognized as a slow-evolving lophotrochozoan that attracts increasing attention as a valuable model for evolutionary and developmental research. Here, we analyzed its immune-related transcriptome. For targeted identification of immune-induced genes we injected bacterial lipopolysaccharide, a commonly used elicitor of innate immune responses, and applied the suppression subtra...

Jones Ray B, and O'Connor Anita, and Brelsford Jade, and Parsons Neil, and Skirton Heather

<p>Abstract</p> <p>Background</p> <p>Better use of e-health services by patients could improve outcomes and reduce costs but there are concerns about inequalities of access. Previous research in outpatients suggested that anonymous personal email support may help patients with long term conditions to use e-health, but recruiting earlier in their 'journey' may benefit patients more. This pilot study explored the feasibility and cost of recruiting patients for an e-health intervention in one prima...

Friederike Barbara Haslbeck, and Hans-Ulrich Bucher, and Dirk Bassler, and Cornelia Hagmann

Abstract Background Preterm birth is associated with increased risk of neurological impairment and deficits in cognition, motor function, and behavioral problems. Limited studies indicate that multi-sensory experiences support brain development in preterm infants. Music appears to promote neurobiological processes and neuronal learning in the human brain. Creative music therapy (CMT) is an individualized, interactive therapeutic approach based on the theory and methods of Nordoff and Robbins. CM...

Shioyama Yasukazu, and Honda Mikihiko, and Abe Hideyuki, and Kambara Tsunehito, and Furuya Nobutaka, and Kamai Takao, and Kaji Yasushi, and Yoshida Ken-Ichiro

<p>Abstract</p> <p>Background</p> <p>Single minimum incision endoscopic surgery (MIES) involves the use of a flexible high-definition laparoscope to facilitate open surgery. We reviewed our method of radical nephrectomy for renal tumors, which is single MIES combined with preoperative virtual surgery employing three-dimensional CT images reconstructed by the volume rendering method (3D-CT images) in order to safely and appropriately approach the renal hilar vessels. We also assessed the usefulne...

Chambliss Walter, and Kothari Shil, and Enonchong Ebangha, and Oben Julius, and Garrison Robert, and Dolnick Deanne

<p>Abstract</p> <p>Background</p> <p>The objective of this clinical study was to assess the potential benefit of a dietary supplement, NP 06-1, on cardiovascular protective properties in overweight and normal weight adults diagnosed with osteoarthritis of the knee.</p> <p>Methods</p> <p>An 8-week, placebo-controlled, randomized, double-blind study was conducted with four groups, comparing the effects of NP 06-1 to placebo in overweight and normal weight subjects diagnosed with primary osteoarthr...

Ana Cristina Petry, and Fabiane Abujanra, and Luiz Carlos Gomes, and Horacio Ferreira Julio Jr., and Angelo Antonio Agostinho

The effects of the duration of the floods on abiotic variables and attributes of species tolerant and intolerant to hypoxia (STH and SIH respectively) were evaluated in rivers and lakes of the upper Paraná River. Fish were sampled once a year, in six sampling stations, during the high water period from 2000 to 2003. There were overall reductions in dissolved oxygen levels and increases in transparency of water in lakes in years of moderate floods. The duration of floods influenced species differ...

Ferhat Kalaycı, and Sabri Bilgin, and Osman Samsun, and Necati Samsun

F. A. Moraga, and N. Urriola-Urriola

Abstract Previous studies performed in intertidal fish (Girella laevifrons),as well as marine fish (Isacia conceptionis), showed that acetylcholine (ACh) produced contractions mediated by cyclooxygenases that were dependent on the area and potency of contraction in several arterial vessels. Given that the role of nitric oxide is poorly understood in fish, the objective of our study was to evaluate the role of nitric oxide in branchial afferent (ABA), branchial efferent (ABE), dorsal (DA) and mes...

P. Yan, and W. Hou, and G. Feng

A new detection method has been proposed to study the transition process of abrupt climate change. With this method, the climate system transiting from one stable state to another can be verified clearly. By applying this method to the global sea surface temperature over the past century, several climate changes and their processes are detected, including the start state (moment), persist time, and end state (moment). According to the spatial distribution, the locations of climate changes mainly...

FAN Miao, and XU Yichuan, and XIE Dingjun, and PENG Hui

<b>[Objectives]</b> This paper concerns about test set optimization and test sequence optimization for system-level testability analysis. <b>[Methods]</b> The Discrete Bat Algorithm(DBA)is used to acquire the optimal complete test set and test sequence for each type of fault based on a multi-signal flow graph model. The convergence speed of the algorithm is accelerated while the optimization accuracy is guaranteed. Taking warship combat systems as the research object, such main indexes as fault ...

M. A. Putanov, and M. A. Sokolova, and P. I. Lenkin, and V. Yu. Slastilin, and I. G. Baskakova, and A. N. Kiriluk, and D. N. Kazarinov, and K. M. Checkaya, and T. S. Isakova, and M. A. Rumyanceva, and M. Yu. Kirov

<p><strong>Aim.</strong> The study was designed to evaluate the efficacy of polypeptide neuroprotection using brain protein “Cellex” for prevention of postoperative cognitive dysfunction after cardiac surgery.<br /><strong>Methods.</strong> Our study included 60 patients undergoing elective cardiosurgical operations, who were randomized into two groups. In the “Cellex” group, the patients received 1.0 ml of “Cellex” subcutaneously daily during 8 days, beginning from the preoperative day, while t...

Francesca Gizzi, and Ludovica de Mas, and Valentina Airi, and Erik Caroselli, and Fiorella Prada, and Giuseppe Falini, and Zvy Dubinsky, and Stefano Goffredo

Abstract Anthropogenic carbon dioxide (CO2) emissions and consequent ocean acidification (OA) are projected to have extensive consequences on marine calcifying organisms, including corals. While the effects of OA on coral calcification are well documented, the response of reproduction is still poorly understood since no information are reported for temperate corals. Here we investigate for the first time the influence of OA on sexual reproduction of the temperate azooxanthellate solitary sclerac...

Duílio M. Z. de A. Silva, and Ricardo Utsunomia, and Francisco J. Ruiz-Ruano, and Sandro Natal Daniel, and Fábio Porto-Foresti, and Diogo Teruo Hashimoto, and Claudio Oliveira, and Juan Pedro M. Camacho, and Fausto Foresti

Abstract The high-throughput analysis of satellite DNA (satDNA) content, by means of Illumina sequencing, unveiled 45 satDNA families in the genome of Astyanax paranae, with repeat unit length (RUL) ranging from 6 to 365 bp and marked predominance of short satellites (median length = 59 bp). The analysis of chromosomal location of 35 satDNAs in A. paranae, A. fasciatus and A. bockmanni revealed that most satellites are shared between the three species and show highly similar patterns of chromoso...

Jonás I. Silva-Marrero, and Alberto Sáez, and Albert Caballero-Solares, and Ivan Viegas, and María Pilar Almajano, and Felipe Fernández, and Isabel V. Baanante, and Isidoro Metón

Abstract Background The impact of nutritional status and diet composition on mitochondrial oxidative phosphorylation (OXPHOS) in fish remains largely unknown. To identify biomarkers of interest in nutritional studies, herein we obtained a deep-coverage transcriptome by 454 pyrosequencing of liver and skeletal muscle cDNA normalised libraries from long-term starved gilthead sea bream (Sparus aurata) and fish fed different diets. Results After clean-up of high-throughput deep sequencing reads, 699...

Zeltia Torrecilla, and Andrés Martínez-Lage, and Alejandra Perina, and Enrique González-Ortegón, and Ana M. González-Tizón

Abstract Background The maintenance of species and the promotion of speciation are closely related to chromosomal rearrangements throughout evolution. Decapoda represents the most species-rich order among crustaceans and, despite its ecological and economic importance, little is known about decapod karyology. We aim at cytogenetically characterizing two sympatric prawn species. Results Analysis of mitotic metaphases and meiotic diakinesis of the common prawn Palaemon serratus and the rockpool pr...

Wenteng XU, Songlin CHEN

Genomics focuses on dissection of genome structure and function to provide a molecular basis for understanding the genetic background. In a pivotal step, the expense of whole genome sequencing has been largely eliminated by the rapid updating of sequencing technology, leading to increasing numbers of decoded genomes of aquatic organisms, driving the aquaculture industry into the genomic era. Multiple aquatic areas have been influenced by these findings, such as accelerated generation shift in th...

Sohan L Solanki, and Jeson R Doctor, and Savi J Kapila, and Anuja Jain, and Malini Joshi, and Vijaya P Patil

Background: Anteroposterior (AP) diameter of internal jugular vein (IJV) and its relative position with carotid artery (CA) varies in the triangle formed by two heads of sternocleidomastoid muscle, which is the site of insertion of needle for IJV cannulation. This study assessed the maximum AP diameter of the IJV in supine and Trendelenburg positions and during Valsalva maneuver (supine position) at the apex, middle, and base of the triangle and to study the relationship of the IJV with the CA. ...

Kh. Arkhipova, and V. Rizun, and A. Martynov, and R. Godunko

During the last 150 years, Lviv scientific and educational institutions are the centers of active investigations on the aquatic insects. Diduszycki’ Museum became the center of systematic study of aquatic insects. As a result, important historical collections of taxonomic groups of insects have been accumulated primarily thanks to efforts of J. Dziędzielewicz, M. Łomnicki and J. Łomnicki. Studies started up in the 1960’s and continued until the First World War, and were restored after 80 years b...

Modjtahedi BS, and Chu K, and Luong TQ, and Hsu C, and Mattox C, and Lee PP, and Nakla ML, and Fong DS

Bobeck S Modjtahedi,1,2 Katherine Chu,1 Tiffany Q Luong,2,3 Chuyni Hsu,2,3 Cynthia Mattox,4 Paul P Lee,5 Mamdouh L Nakla,6 Donald S Fong1&ndash;3 1Department of Ophthalmology, Southern California Permanente Medical Group, Baldwin Park, CA, USA; 2Eye Monitoring Center, Kaiser Permanente Southern California, Baldwin Park, CA, USA; 3Department of Research and Evaluation, Southern California Permanente Medical Group, Pasadena, CA, USA; 4New England Eye Center, Tufts University School of Medicine, B...

Helen Tilbrook, and Laura Clark, and Liz Cook, and Martin Bland, and Hannah Buckley, and Ian Chetter, and Jo Dumville, and Chris Fenner, and Rachael Forsythe, and Rhian Gabe, and Keith Harding, and Alison Layton, and Ellie Lindsay, and Catriona McDaid, and Christine Moffatt, and Debbie Rolfe, and Illary Sbizzera, and Gerard Stansby, and David Torgerson, and Peter Vowden, and Laurie Williams, and Robert Hinchliffe

Background: Venous leg ulcers (VLUs) are the most common cause of leg ulceration, affecting 1 in 100 adults. VLUs may take many months to heal (25% fail to heal). Estimated prevalence is between 1% and 3% of the elderly population. Compression is the mainstay of treatment and few additional therapies exist to improve healing. Two previous trials have indicated that low-dose aspirin, as an adjunct to standard care, may improve healing time, but these trials were insufficiently robust. Aspirin is ...

Hana Bednáříková, and David Smékal, and Pavlína Krejčiříková, and Ivana Hanzlíková

Background: Locally applied vibration has been recently proposed as a treatment for pain relief. Objective: The aim of this study was to assess the effect of specific vibration therapy using the Redcord Stimula device on reduction of pain in patients with chronic low back pain. Methods: The study included 14 subjects aged 16-59 years. Pain was assessed at the baseline and after the therapy using the Short Form McGill Pain Questionnaire as well as with Oswestry Disability Index, pressure pain thr...

Filep Levente, and Illyés László

Problem generators are practical solutions for generating a set of inputs to specific problems. These inputs are widely used for testing, comparing and optimizing placement algorithms. The problem generator presented in this paper fills the gap in the area of 2D Cutting & Packing as the sum of the area of the small objects is equal to the area of the Large Object and has at least one perfect solution. In this paper, the already proposed Upper Deck algorithm is revisited and used to test the prop...