Yu-Yuan Chia, 賈有元

碩士 / 國立中興大學 / 食品科學系 / 92 / Heterotrophic culture has been one of the effective ways to increase the yield and productivity of microalgae. In this study, Chlorella pyrenoidosa NCHU-6, a useful green algal strain with heterotrophic growth function and high yield, was used. At first, optimization of cultivation conditions in shaking flasks in the absence of light was studied so that the results obtained may offer the reference for the subsequent determin...

Pei-LingTung, 董珮伶

碩士 / 國立成功大學 / 環境工程學系 / 104 / Cyanobacteria blooms and cyanotoxins have posed a great threat to human beings for many years, causing liver and renal pathology, mainly through oral intake of drinking water contaminated by the toxins. However, in a few recent studies, inhalation of aerosolized cyanobacteria and cyanotoxins is considered to be another pathway for exposure to cyanotoxins. Therefore, establishing a feasible and efficient detection method for the air samples will provide a better basis...

Cho-Hsun Sung, 宋卓勳

碩士 / 國立中正大學 / 化學所 / 98 / Hot water extract of Chlorella（HWEC） has shown to protect cells from the UV-induced cytotoxicity. The purpose of this study aims to develop an optimal condition to isolate highly purified active substances from the commercial spray-dried HWEC powder. The separation of bioactive substances by isoelectric point precipitation, ultra filtration and dialysis methods was implemented. This inhibition potential of bioactive substances on UV-induced cytotoxicity was evaluated by ...

Chun-Huan Chou, 周君奐

碩士 / 國立臺灣海洋大學 / 食品科學系 / 99 / This study aims to investigate the effects of food component on cell migration in human hepatoma cells. Previous studies revealed that mitochondrial dysfunction-induced amphiregulin (AR) upregulation mediates cell migration and chemoresistance in HepG2 cells. Moreover, mitochondrial dysfunction induced intracellular hydrogen peroxide overproduction and calcium mobilization may modulate AR induction in this setting. In this study, the mitochondrial dysfunction was def...

Ting-Ju Yang, 楊婷如

碩士 / 靜宜大學 / 食品營養研究所 / 99 / Spirulina platensis contains abundant of protein, vitamin B12 and C-phycocyanin (C-PC). It was demonstrated that Spirulina platensis and C-PC have potently physiological properties, such as excellent antioxidant ability, neuron protection, virus inhibition and lessen the inflammation. However, theeffects of Spirulina platensis and C-PC on the anti-inflammatory activity of microglial cells is unclear. In this in vitro study, we aimed to evaluate the anti-inflammatory an...

Nian-cih Chang, 張念慈

碩士 / 靜宜大學 / 食品營養研究所 / 99 / Salicylates, also known as aspirin, is known to induce tinnitus. However, the mechanism of generation of tinnitus induced by salicylate is still unclear. Tinnitus is a non-observable phantom sensation, and had no effective treatment until now. Spirulina platensis showed good antioxidant capacity, anti-inflammation and neuroprotective effect. The purpose of this study was to examine the effects of Spirulina platensis on salicylate-induced tinnitus in senescence accelera...

Wu, Hsiaomei, 吳小梅

碩士 / 靜宜大學 / 食品營養學系 / 99 / Chlorella sp. is known to have many kinds of healthy functionality, partly relating to their potential inhibition activity against glycosidase enzymes. This study was to investigate the major chemical compositions, antioxidant activities (DPPH and ABTS free radicals), and inhibitory activities against glycosidase (alpha-glucoside, beta-glucoside and beta-glucuronidase) of various solvent extracts and fractions from Chlorella sorokiniana, in order to develop isolation pr...

Li-Hsien Huang, 黃俐嫻

碩士 / 國立臺灣大學 / 微生物與生化學研究所 / 98 / SUMO (small ubiquitin-like modifier) is one of the ubiquitin-like proteins, which can covalently attach to target proteins for post-translational modification. SUMOylation cascade includes SUMO E1 activating enzyme, E2 conjugating enzyme and E3 ligases. SUMO E1 activating enzyme is a heterodimer composed of SAE1 (sumo activating enzyme subunit 1) and SAE2 (sumo activating enzyme subunit 2). I initially performed the BLAST search by using the SUMO E1 sequences of S...

Siao-Jing Tang, 唐曉菁

碩士 / 國立臺灣大學 / 微生物與生化學研究所 / 98 / Ubiquitin and ubiquitin-like protein (Ubl) modification systems, composed of specific peptidases, E1 activating enzymes, E2 conjugating enzymes and E3 ligases, can specifically conjugate ubiquitin and Ubl to the lysine residues of target proteins. Studies of ubiquitin and Ubl-specific peptidases (USPs) in human, Arabidopsis and yeast have been reported in the literatures. However, the ubiquitin and USPs in Chlamydomonas reinhardtii have not been revealed. This stu...

Yu-Chan Chu, 朱育嬋

碩士 / 靜宜大學 / 食品營養研究所 / 95 / Cancer is the major death cause in Taiwan. Recently, there is an increase interest in the study how to prevention or delay the hepatoma development. Chlorella has been reported to show antioxidant activity and anticancer functions. In this study, we will examine the antioxidant activities of Chlorella and possible apoptosis mechanim in human hepatoma cell lines (Hep G2 cells). The results demonstrated that 80% ethanolic extracts from commercial granule chlorella prod...

Ya-Ling Tseng, 曾雅伶

碩士 / 臺灣大學 / 微生物與生化學研究所 / 98 / The SUMO E3 ligase involves in the last step of sumoylation. In addition to faciliate sumoylation and increase specificity for the targets, SUMO E3 ligases modulate a wide range of physiological functions. There are many sumoylated proteins in the cells, but only three kinds of SUMO E3 ligases have been shown in the literatures. Notably, the study of SUMO E3 ligase in Chlamydomonas reinhardtii has not been reported. In this study, using the Arabidopsis SUMO E3 ligas...

Jiang, Kun-yu, 江坤諭

碩士 / 靜宜大學 / 食品營養學系 / 99 / This study was to investigate the molecular property and in vitro immunostimulatory effect of hot water extract (WS) and destarched WS (WS-ds) of Chlorella sorokiniana, and their molecular fractions as well as modified WS-F1 with a certain of organic acids (serine, cysteine, glutamic acid, ascorbic acid, and citric acid). The molecular fractions prepared by tangential flow filtration included WS-F1 (> 100 kDa), WS-F2 (10-100 kDa), WS-F3 (< 10 kDa), WS-ds-F1, WS-ds-F2, a...

Wen-Yung Hung, 洪文詠

碩士 / 國立臺灣海洋大學 / 食品科學系 / 99 / The domestic cultivated Chlorella sorokiniana as a material , the inhibitory effects of α-glucosidase and α-amylase of Chlorella sorokiniana hydrolysates (hydrolyzed by cellulase and protease) were investigated, and purified bioactive substances from hydrolysate having the highest α-glucosidase and α-amylase inhibitory activity to evalvate the physiological effect on regulation of blood sugar. When adding 5% cellulase and 2% protease in the Chlorella hydrolysates (pu...

Wan-Ron Lin, 林宛柔

碩士 / 國立中興大學 / 食品科學系 / 93 / Previous study regarding determination of heterotrophic cultivation conditions in shaking flasks for a useful algal strain, Chlorella pyrenoidosa NCHU-6, was continued. Medium optimization using experimental designs was performed further in this study. Moreover, the optimum medium obtained was used for subsequent semicontinuous cultivation of the alga to improve further the algal growth and cellular chlorophyll content by using the table-top fermentor without illuminat...

Wei-Chih Wang, 王偉至

碩士 / 大同大學 / 生物工程學系(所) / 107 / Chlorella contains high amounts of amino acids, unsaturated fatty acids, dietary fibers, minerals and vitamins. It is also rich in Chlorella Growth Factor (C.G.F). Chlorella can assist to lift levels of anti-atheroscloresis, anti-diabetics and antioxidation. And it helps to remove intestinal heavy metals from human body. Ingestion of C.G..F can help to strengthen immune system, promoting cell growth. It is also with high efficacy in boosting cell growth. The aim of ...

Cheng-chi Hsiao, 蕭丞祺

碩士 / 國立中山大學 / 海洋環境及工程學系研究所 / 97 / The crisis of the water resources become a serious problem in recent years. Besides the global warming the problem mostly comes from quick population growth, intense industrial developments and low efficiency agricultural implementations. Biofilters are widely been used to either reduce pollution loads or also as a water conservation tool. And the vertical-flow biofilters act as a kind of bio-filter has gain the advantages of low maintenance, small footprint, gr...

Shan-ying Yang, 楊珊盈

碩士 / 靜宜大學 / 食品營養研究所 / 98 / Tinnitus is a phantom sensation of sound in the absence of external stimulations while its pathogenesis is unclear and effective treatment has not been developed yet. To approach the phantom sensation, we aimed to develop a SAMP8 mice behavioral model of conscious tinnitus using salicylate, an active component of aspirin known to induce tinnitus. The purpose of this study was to examine the effects of Spirulina and C-phycocyanin on tinnitus in senescence accelerated pr...

Pan, KuenMing, 潘崑銘

碩士 / 輔仁大學 / 物理學系 / 101 / In this work, the argon ion green laser (514.5 nm) or near-infrared laser (785 nm) was used to be the source for Raman tweezers in order to understand the structure through the vibrational modes of molecules in the bacterium. There are two kinds of bacteria in our experiment, one is oil-producing microorganisms and the other is Thermosynechococcus elongates (TA-01) from hot spring. Of the Raman spectra with green source, the main bands are 1002 cm-1(δ(C-CH3)), 1155 cm-1...

蕭秀玟

碩士 / 國立臺灣海洋大學 / 食品科學系 / 96 / Chlorella was fermented with five mixed lactic acid bacteria for up to 40h at 42℃. A protease was added at the beginning of fermentation. The supernatant fraction was separated from the fermented Chlorella and freeze-dried. The inhibitory effect of supernatant against angiotensin I converting enzyme (ACE) and production of γ- aminobutyric acid (GABA) were investigated. Chlorella (with pulverized cell) was fermented with protease-facilitated. As the fermentation time ...

Ti-I Huang, 黃娣儀

碩士 / 台北醫學院 / 保健營養學研究所 / 88 / ABSTRACT The effects of chlorella on the lipid metabolism in Wistar male rats were investigated in this study. Two different feed regiments were designed to test the hypolipidemic function of chlorella. In the first regiments, chlorella (0%,1%, 5% and 10%) was added to the high fat and high cholesterol diet at the same time for feeding normal rats, and prevention of hyperlipidemia by chlorella was tested(testⅠ).In the second regiment, chlorella (0%,1%, ...

Jeng-Long Sheu, 許正隆

碩士 / 國立清華大學 / 化學工程學系 / 89 / The energy on the Earth is relatively limited. Therefore, in recent years everybody pay attention to the application and development of renewable resource gradually. Microalga that have a wide range of application are renewable resource. The biomass of microalga include abundant protein, vitamin and other materials that can provide to increase in the food, animal feed, medicine, health care food etc. Easier cultivation and faster growth would the advantage of microalg...

Pi-Yu Liu, 劉碧玉

碩士 / 國立臺灣海洋大學 / 食品科學系 / 100 / pulverized chlorella and freshwater clam were used as new material in this study. Pulverized chlorella were hydrolyzed by cellulase and protease at 50℃ for 3 hours. The freshwater clam muscle was extracted using hot water. The residual meat was first freeze-dried, then hydrolyzed at 50oC by protease to obtain freshwater clam hydrolysate. The inhibitory effect of Chlorella (CH) and freshwater clam hydrolysates (PX) on activity of α-glucosidase and DPP4 (dipepidy pept...

Yun-Yi Chang, 張紜漪

碩士 / 國立臺灣海洋大學 / 食品科學系 / 101 / Chlorella, rich in proteins, peptides, chlorophyll, vitamins and minerals, is anexcellent material for the production of functional foods. However, the rigid cell wall cannot be easily digested and absorbed, which consequently lowered its nutritional value. To rupture the cell walls of chlorella, it was hydrolyzedwith 150 U/g of cellulase and 1% protease at 50oC. According to the scanning electron microscope photograph, obvious lysis of cell walls was observed after...

Sun Tsai-Chien, 孫財前

碩士 / 靜宜大學 / 食品營養研究所 / 94 / Abstract This study was to investigate the antioxidant activities of Chlorella water extracts with various extraction conditions by the central composite design, where the independent variables were extraction temperature and time. The data were statistically analyzed with response surface method to find the optimal extraction condition for a better antioxidant activity. The results of antioxidation measurements indicated that all extracts showed a good DPPH-radical ...

Hui-pin Chen, 陳卉頻

碩士 / 國立臺灣科技大學 / 化學工程系 / 97 / The purpose of this research is (1) to investigate the effect of environmental factors such as light intensity, and chemical factors such as glucose and NaHCO3 on the growth of cyanobacteria of Synechocystis sp. PCC 6803 and (2) to study the expression of Enhanced Green Fluorescent Protein and Vitreoscilla Hemoglobin. Synechocystis sp. PCC 6803 grew well under photoautotrophic condition at light intensity of 34 μE m-2 s-1。The glucose can be used as carbon source with...

Cheng-I Liu, 劉正儀

碩士 / 臺北醫學大學 / 醫學研究所 / 92 / Chlorella vulgaris, a unicellular green algae, contains rich nutrients and has been used widely as a health food supplement. Studies on Chlorella’s health benefits have been mainly focused on its effects as an antioxidant and a weight loss meal-replacement, and on the improvement of hypertension and hyperlipidemia.Currently, it has been also demonstrated that hot water extracts of Chlorella vulgaris can boost host’s defenses against tumors, and viral and intracellular ...

Chong-bin Su, 蘇重賓

碩士 / 國立中山大學 / 機械與機電工程學系研究所 / 103 / In the wake of highly development in the physical civilization and the prosperity of industry and commerce, humans are confronting with huge pressure on energy and environments, whereas the natural resources will be eventually depleted. Meanwhile, due to carbon dioxide emissions greatly increased in recent years, which results in global warming and brought to a negative greenhouse phenomenon. Because of growing up by the algae itself, it has the ability to perf...

Ya-Ching Hsu, 許雅淨

碩士 / 靜宜大學 / 食品營養研究所 / 97 / Chlorella is a unicellular green microalgae that contains multiple nutrients. Previous studies have demonstrated that chlorella shows antioxidant, antihypertensive, antilipidemic, anti-inflammatory and antitumor effects. The purpose of this study was to investigate the effects of chlorella extracts on learning and memory ability, and antioxidant status in senescence-accelerated mice (SAMP8). Three and six-month-old SAMP8 male and female mice were used in this study. SA...

Chang, Yuan-Ming, 張元銘

博士 / 國立屏東科技大學 / 生物資源研究所 / 104 / Microalgae contain many nutrients such as protein and lipid, and possess potential advantages of easy cultivation and rapid growth. Therefore, they have become the most valuable precursors for the development of health-care medical foods or products. On the other hand, microalgal residue will be inevitably generated from the manufacturing process of microalgae-derived products at a certain percentage. This biomass residue is currently reused as feed and fertilizer...

金惠明

碩士 / 國立臺灣海洋大學 / 食品科學系 / 99

Mei-Chih Lien, 連美智

碩士 / 國立臺灣海洋大學 / 食品科學系 / 99

Chi–Wei Huang, 黃知偉

碩士 / 靜宜大學 / 食品營養研究所 / 99 / Tinnitus is a phantom sensation of sound in the absence of external stimulations. Serious tinnitus may affect emotion, concentration, and even the quality of life. However, the treatments of tinnitus need further study. The purpose of this study was to develop a behavioral model of conscious tinnitus with SAMP8 mice induced by salicylate, and evaluated the effects of Spiulina water extract on relative receptors. Three-month-old SAMP8 mice were randomly divided into nor...

Wei Ming Lu, 盧偉銘

碩士 / 國立中興大學 / 環境工程研究所 / 81 /

Kuan-Ting Pei, 裴冠婷

碩士 / 國立臺灣海洋大學 / 食品科學系 / 98 / The pulverized Chlorella was the experimental material. The differences between the hydrolysis fermentation and the fermentation after followed hydrolysis on the inhibitory effect of the supernatant against angiotensin I-converting enzyme (ACE) and production of γ-aminobutyric acid (GABA) were investigated. The ACE IC50 of the supernatant fermented-after-hydrolyzed increased from 0.08 to 0.10 mg peptide/mL, and the content of GABA increased from 104.6 to 117.1 mg/100...

Wei-Syun Jiang, 蔣維訓

碩士 / 靜宜大學 / 食品營養學系 / 100 / It is known that the biopolymers (mainly glycoproteins) in hot water extracts of Chlorella sp. show in vitro and in vivo immunostimulatory activities. The immunostimulatory activities may be influenced by coexisting starch in the extract and processing conditions during extraction or purification of the active glycoproteins involved. Therefore, the aim of this study was to investigate the effects of de-starching treatment, thermal treatment, and the variety and concent...

Hsiao-Ju, 李効孺

碩士 / 中山醫學大學 / 營養學研究所 / 100 / In this study, Chlorella water extracts was used for determining anti-inflammation. Results showed that Chlorella water extracts inhibited iNOS and COX-2 protein expression on LPS-induced RAW 264.7 macrophage. To further evaluate the anti-aging effect of Chlorella water extracts in human. A randomized and placebo-controlled study was designed. Forty-four subjects (11 males and 33 females) were completed involved in this study. The total experimental period was 180 da...

Jine-Yung Huang, 黃俊揚

碩士 / 國立東華大學 / 海洋生物科技研究所 / 96 / In continuing search the bioactive secondary metabolites from marine microorganism, we found that the extracts of marine cyanobacteria Lyngbya majuscula, collected from Ryukyu Island, showed significant anticancer and anti-dialetes activities. Through bioassay-guided separation, we isolated four malyngamides, including three new compounds, malyngamide Z (1), malyngamide X (2), malyngamide 1 (4) and a known compound, isomalyngamide A (3). We also isolated four aplys...

Chun-HuiYu, 余俊輝

碩士 / 國立成功大學 / 工程科學系碩博士班 / 99

CAI, XING-ZHEN, 蔡幸真

碩士 / 國立中興大學 / 植物學研究所 / 73 /

HUANG, SHU-WEI, 黃書瑋

博士 / 中國文化大學 / 實業計劃(農學組)研究所 / 73 /

Huang, Wen-Juan, 黃玟娟

碩士 / 國立臺灣大學 / 農業化學研究所 / 65 /

CHEN, LING-LAN, 陳鈴蘭

碩士 / 國立臺灣大學 / 植物學研究所 / 73 / Anabaena HA101, HA405 和HA501 在液態通氣培養下，只HA101 可以生長穩定且形成 均勻懸液，為較佳的實驗材料。HA101 在MBGo-11 培養液中，有較佳的生長速率，而 在SMo 培養液中，則有較好的固氮活性。在SMo 培養液中PH值鹼性，HA101 及HA405 的固氮活性較好。在培養液不含任何氮源情況下，藍綠藻固氮作用與其異胞數目有密 切關係，但於異胞老化時，二者之間的相關性則減少。含氮培養液中，ＮＯ或Ｎ Ｈ均可抑制異胞之形成與固氮之固氮活性，而ＮＨ對藍綠藻之影響比ＮＯ 對藍綠藻之影響大。藍綠藻固氮作用與光合作用密切相關，而與氫氣產生量成負 相關的現象。固氮作用所需能量主要來源是呼吸作用。用ＫＣＮ及ＣＯ抑制藍綠藻固 氮作用的程度比用ＤＣＭＵ藥品...

Li-Shing Huang, 黃立心

碩士 / 國立臺灣大學 / 化學研究所 / 91 /

Pan, Je-Min, 潘哲旻

碩士 / 國立臺灣海洋大學 / 商船學系 / 107 / The ship transportation industry is a high-risk industry. In recent years, IMO has spared no effort to reduce the ship accident rate, but the sea accident rate is still high. Even under many safety-related regulations and regulations, it is still unable to effectively prevent the occurrence of marine accidents. According to the accident statistics published by IMO, human error is the primary cause of anecdotes. Compared with mechanical or operational technical neglig...

Chiang, Wen-Chia, 江文嘉

碩士 / 國立臺灣師範大學 / 體育學系 / 97 / The study was based on the theory of Somatics and discussed senior high school rowers’ ability of body awareness throughout the somatic education courses in order to gain a better understanding of rowers’ changes in breathing, muscle tension status, body usage, awareness of abnormal body conditions, and awareness of body control. In addition, according to the rowers’ development in body awareness, the study focused on the issue of the applicability of somatic educatio...

Kin-Hui Fan, 范健栩

碩士 / 國立臺灣科技大學 / 設計系 / 107 / Science fiction is a movie genre that garners the best box office performance. Science fiction movies not only provide pure entertainment and reflect contemporary trends, they also indicate willingness to explore ideals and visions of future social culture and future technological development trends. The fantasies and ideas of future lifestyles and problem solving methods in movies portray the blueprint of human imagination about the future world, and satisfy public e...

Xiang-Jun Chen, 陳翔竣

碩士 / 國立中山大學 / 資訊工程學系研究所 / 105 / Today, we have many kinds of the 3C device like smart phone or notebook. We use these for work, communication, and entertainment. In the past years, the device that detects real world information to interact with computer graphic becomes popular. Many of these devices, like Kinect, Leap Motion and HTC Vive, use multiple sensors to generate the 2D image with depth map. With the depth map, the software can combine two scenes into one, that allows the user to intera...

Lee, Yu-Shun, 李雨順

碩士 / 國立屏東科技大學 / 環境工程與科學系所 / 106 / In 2009, Typhoon Morakot caused numerous landslides at the upstream mountainous area of the Kaoping in Taiwan. The heavy rain caused by the typhoon washed soil and rocks downstream, and after the river water evaporated, the debris-flow deposits formed a large bare land on the riverbed. In recent years, river management authorities have attempted to reduce bare riverbed by dredging, covering bare riverbed with straw blankets, and planting Pennisetum alopecuroides...

高雅琦

碩士 / 國立彰化師範大學 / 環境暨觀光遊憩研究所 / 98 / The development of settlements in rural areas is often nearby the regional drainage channels.Accompanying with the development of the commercial and industrial activities and the growth of the population, the extent of damage to the regional drainage environment is more severe than anytime before. Due to the complexity of interaction between water environment and the Human beings, it is wise to investigate the re lationships between environmental perception, at...

Ka-wa Chan, 陳嘉華

碩士 / 國立中央大學 / 大氣物理研究所 / 100 / Pearl River Delta (PRD) is located in southern China near the coastline. It is one the most populated regions in China with more than 50 million people living in this area. Through the last two decades, PRD region has experienced the unprecedented land-use and land-cover changes as a result of rapid economic development and urban expansion. Its possible impact on regional air quality and climate change is a major concern of the national government as well as the glo...