Chen, Ariel Yu-Zhen, 陳俞蓁

碩士 / 國立交通大學 / 教育研究所 / 103 / The purpose of this study was to investigate the effects of integrating dynamic concept maps with IRS on elementary school students’ motivation and anti-phishing learning outcome. This study employed the quasi-experimental design. A total of 130 fifth-grade students participated in this study, divided into three groups: a control group (traditional image-text), an experimental group I (static concept maps), and an experimental group II (dynamic concept maps). The inst...

Chih-Yuan Chen, 鄭智元

碩士 / 國立屏東科技大學 / 農企業管理系所 / 103 / In this study, in order use questionnaire to explore the relationship tourists travel motivation, recreation experience, travel satisfaction and revisiting intention on “The One And Only Crocodile Zoological Farm”. Statistical analysis of the study was descriptive statistics analysis, reliability analysis, t test, ANOVA, regression analysis and path analysis. The total recovery of 400 valid questionnaires, reliability facets are all on good reliability standards. ...

Ji-Fan Lin, 林致凡

博士 / 國防醫學院 / 生命科學研究所 / 96 / Increased expression of insulin-like growth factor II (IGF2) has been well documented in human hepatitis, hepatoma and hepatocellular carcinoma (HCC). Recent microarray study demonstrated elevated IGF2 level in human steatosis. However, IGF2 is the causative agent or just ensures maintenance of proliferation of neoplastic cells as a secondary signal remains unclear. Utilizing the previously established GFP-liver transgenic zebrafish, in which changes in liver morpholo...

Chung,Wen-Ling, 鍾文玲

碩士 / 國立臺灣大學 / 園藝學系 / 81 /

Meei Mei Chen, 陳媺玫

博士 / 國立臺灣大學 / 動物學系 / 81 / SB細胞株源自青魚鰾組織，在初級細胞培養時，即表現出喪失停泊依賴性 ，喪失接觸抑制性，血清依賴性降低及高群落形成率等腫瘤細胞特性，以 倒立顯微鏡觀察，SB細胞以纖維母細胞為主，其間夾雜許多巨大細胞。以 Acridine orange 染色，並以螢光顯微鏡觀察，可觀察到在這些巨大細胞 細胞質的位置有黃綠色包涵體，應為雙股核酸病毒的包涵體。在掃描式電 子顯微鏡下，SB細胞表現鋪展不良，富於長微絨毛等強轉型細胞特性。SB 細胞的培養液接種於CCT及TO-2細胞，導致嚴重細胞病變。這些結果顯示 ，SB細胞源自腫瘤組織，並有雙股核醣核酸病毒的持續性感染。以穿透式 電子顯微鏡觀察此尾青魚之組織，在前腎可觀察到細胞質空泡化，細胞核 膜增生等病變，並可觀察到二十面體病毒的存在。 SB細...

LIU, ZHEN, 劉貞

碩士 / 輔仁大學 / 生物學研究所 / 82 /

施勇綸

博士 / 國立陽明醫學院 / 微生物暨免疫學研究所 / 81 /

Kun-Han Yang, 楊坤翰

碩士 / 國立臺灣大學 / 口腔生物科學研究所 / 102 / he Six1 homeobox gene plays a critical roles in vertebrate organogenesis. Mice deficient for Six1 show severe defects in organs such as skeletal muscle, kidney, thymus, sensory organs and ganglia derived from cranial placodes. Mutations in human SIX1 cause Branchio-Oto-Renal syndrome(BOR), characterized by hearing loss and branchial defects. Six1 genes are hypothesized to play important roles in organgenesis and cell differentiation. Depending on the previous st...

Chih-Hsuan Teng, 滕致萱

碩士 / 國立臺灣大學 / 生命科學系 / 102 /

Huey-Jen Wang, 王惠禎

碩士 / 國立臺灣大學 / 臨床牙醫學研究所 / 102 / Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is one of the main side effects of bisphosphonate therapy (BPT). To date, there is no effective therapy of the BRONJ. Nitrogen-containing bisphosphonates (N-BPs) target to the inhibition of pyrophosphate synthase (FPPS) in the mevalonate pathway. Consequently, decreased synthesis of the downstream metabolites, geranylgeraniol (GGOH) and farnesol (FOH), is believed to largely account for the development of BRON...

Dun-RongYou, 游惇蓉

碩士 / 國立成功大學 / 環境工程學系 / 102 / Impact of hydrogen peroxide on a geosmin-producing cyanobacterium Anabaena circinalis under light conditions is investigated. A UV and a high-pressure Hg lamps were used as the light sources. The experimental results revealed that the light source, light intensity, hydrogen peroxide dosage and hydroxyl radical concentration are important factors for cell lysis. Three Chick-Watson type models were used to reasonably describe the experimental data for the kinetics of c...

Li-Wei Kuo, 郭力瑋

碩士 / 國立臺北科技大學 / 生物科技研究所 / 102 / KRAS or BRAF mutation has an important role in the epidermal growth factor receptor pathway (EGFR pathway). According to our pervious findings, up-regulation of the expression of miR-378 by lauric acid in KRAS or BRAF mutant CRC (Colorectal cancaer) cells will further trigger the cell’s sensitivity of anti-EGFR antibody. Herein, we replaced the lauric acid (saturated fatty acid) by EPAee (unsaturated fatty acid), an FDA-approved compound, and used CRC cells as a m...

Yu, Chu-Hung, 游礎鴻

碩士 / 國立臺灣海洋大學 / 機械與機電工程學系 / 102 / This study adopted the microfluidic chip integrated with the phosphorescence phase difference optical detecting system to develop the device for detecting local distribution of blood and oxygen in the body of juvenile fish of single zebra fish. The microfluidic detecting platform combined with two components: the pneumatic actuator positioning zebra fish microfluidic chip and the phosphorescence phase difference optical inspection system. T...

Lee, Hsiao-Chien, 李筱茜

碩士 / 國立臺灣海洋大學 / 食品科學系 / 102 / Temperature of aquatic environment is important for ensuring the normal metabolism of aquatic animals. The purpose of this study was to evaluate adaptability of the tilapia after feeding the diet containing 1% I-Tiao Gung (GTE) ethanolic extract for 4 - 6 weeks followed by heat stress. After tilapia was exposed to chronic temperature stress (25 to 37oC, 2oC/h, 37oC for 24 h, then to 9oC within 24 h), or acute temperature stress (sudden heat shock from 25oC to 37oC a...

Pan, Chen-Yu, 潘振宇

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 102 / PPAR-γ (Peroxisome proliferator-activated receptor gamma) is a transcription factor, regulates lipid metabolism and adipocyte differentionaion in human and mice,but in zebrafish it`s still uncertain. In previeus study, over-expression PPAR-γ lead lipid accumulation in mice. Here we eatablish a PPAR-γ over-expressed zebrafish plaform to study lipid metabolism gene network. Over-expressed PPAR-γ leads lipid accumulation in zebrafish. The lipid accumulation level de...

Chuan,Juan-Chung, 阮中權

碩士 / 國立臺灣海洋大學 / 海洋事務與資源管理研究所 / 103 / Diaoyutai Islands are 186 kilometers（102 Nautical mile）from the northeast of Keelung and the inherent territory and traditional fishing operations of Taiwan. Many resources were involved in Diaoyutai Islands dispute, such as sovereignty, seabed resources and fishing resources in surrounding countries, which include Taiwan, Japan and China.China proposed solution to the disputes are“shelving differences and seeking joint development”. While Japan proposed solu...

Yen, Tzu-Chun, 顏自君

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 102 / Ulcerative colitis (UC) and Crohn’s disease (CD) are two types of human inflammatory bowel disease (IBD). Patients with UC present thinner intestinal mucus layer which inspires us to investigate relationship between intestinal goblet cell development and human IBD using zebrafish. We used chemicals including 2,4,6-trinitrobenzene sulfonic acid (TNBS) and Dextran sulfate sodium (DSS) that used in mouse to induce IBD to treat zebrafish embryos. Embryos were treated ...

Lin, Tzung-Yi, 林宗毅

博士 / 國立臺灣海洋大學 / 生物科技研究所 / 103 / The liver plays a vital role in metabolism, detoxification, digestion, and the maintenance of homeostasis. During development, the vertebrate embryonic liver undergoes a series of morphogenic processes known as hepatogenesis. Hepatogenesis can be separated into three interrelated processes: endoderm specification, hepatoblast differentiation, and hepatic outgrowth. Throughout this process, signaling molecules and transcription factors initiate and regulate the coo...

Jheng, Yu-Hsuan, 鄭宇軒

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 102 / Artemia has been used extensively in aquaculture as a fodder for larval fish, shrimp, and shellfish. Epinecidin-1, an antimicrobial peptide, was isolated from grouper (Epinephelus coioides) in 2005. Epinecidin-1 has been previously reported to possess antimicrobial activity against several Gram-positive and Gram-negative bacterial species, including Staphylococcus coagulaes, Pseudomonas aeruginosa, Streptococcus pyogenes, and Vibrio vulnificus. In this study, we ...

Huang, Kuo-Sheng, 黃國勝

碩士 / 國立臺灣海洋大學 / 機械與機電工程學系 / 102 / A combination of a microfluidic device with a light modulation system was developed to detect the oxygen consumption rate (OCR) of a single developing zebrafish embryo via phase-based phosphorescence lifetime detection. The microfluidic device combines two components: an array of glass microwells containing Pt(II) octaethylporphyrin as an oxygen-sensitive luminescent layer and a microfluidic module with pneumatically actuated glass lids above the microwells to c...

Chang, Jui-Ning, 張芮寧

碩士 / 國立臺灣海洋大學 / 食品科學系 / 102 / Temperature control is important for perishable products with short shelf life. Time temperature indicators (TTIs) are used as cost-effective devices to monitor the effect of temperature history on food quality. This study aims to develop a microbial TTI prototype to monitor grouper fillets quality change by using both total aerobic plate count and volatile basic nitrogen as quality indicators and evaluate the applicability of the TTIs as shelf life monitors　under r...

Ya-Jie Yang, 楊雅捷

碩士 / 國立東華大學 / 海洋生物科技研究所 / 100 / Larval development of saddleback clownfish, Amphirpion polymnus, was described and illustrated using dissecting microscope, and surface microstructures of eggs and larval were also observed by using scanning electron microscopy (SEM). The 96 h acute toxicity of ammonia, nitrite and nitrate in juvenile A. polymnus for the water quality management were also evaluated. Under the scanning electron microscopy, fertilized egg was smooth, ellipse shaped, with attachment ...

PENG, CHANG-YANG, 彭昌洋

碩士 / 國立海洋大學 / 水產食品科學研究所 / 77 /

Yi-Hui Wang, 王怡惠

碩士 / 國立彰化師範大學 / 生物技術研究所 / 99 / Copper (Cu) ion is an essential trace element for all organisms, but excess Cu ion exposure can produce oxidative stress and exert a variety of pathological effects. In this study, we treated zebrafish embryos with 2.5-10 ppm Cu ion for 48 h, the survival rate was decreased and the abnormal embryos were increased significantly. LC50 was about 2.5 ppm for Cu ion treated for 48hr. Reactive oxygen species (ROS) was elevated and the level of protein carbonylation and l...

Ai-Yun Chiang, 江艾芸

碩士 / 國立高雄第一科技大學 / 應用德語研究所 / 99 / After the 90s, “Globalism” has been the hottest topic, and translation has become the most important bridge to communicate with other countries and cultures. The invention of the internet has caused the explosion of the media information. Just switch on the TV or computer, you can get the prompt news from the whole world, and TV series, music are also available. According to the explosion of the media information, we need more translation of the multi-media, ex: ...

Yu-Chang Lin, 林育昌

碩士 / 臺北醫學大學 / 醫學科學研究所 / 98 / 生長相關蛋白43（的GAP - 43 ）是一種神經元特異性蛋白，高效表達，在神經生長錐在開發和再生。這是導致軸突延長，突觸可塑性和突觸傳遞的神經系統。此外，動物的行為是依賴於神經迴路。為了排除這種可能性的軸突延伸和突觸傳遞有關的GAP - 43規定的模式動物的行為。在這項研究中，我們使用雙啟動子驅動的zGAP zHuC - 43S41A ， zGAP - 43S41D或zGAP - 43WT基因與綠色熒光蛋白基因表達的記者在神經系統在斑馬魚發育階段。過表達zGAP - 43S41A ， zGAP - 43S41D或zGAP43WT在斑馬魚胚胎形態的缺失造成了一些混亂和在神經軸突的延伸。通過結合觸摸檢測與觀察游泳能力，觸摸靈敏度zGAP - 43S41A ， zGAP - 43S41D和zGAP - 43WT轉基因斑馬魚均高於野生型對照。游泳能力的觀察結果表明， zGAP - 43S41D轉基因斑馬魚有更多的游泳能力比zGAP - 43S41A轉基因斑馬魚和野生型對照。觸覺刺激後，在zGAP - 43S41A轉基因斑馬魚少了游泳的...

黃士豪

碩士 / 國立交通大學 / 應用化學研究所 / 98

Chih-YuHuang, 黃智郁

碩士 / 國立成功大學 / 微生物及免疫學研究所 / 98 / Vibrio vulnificus, a gram-negative estuarine bacterial species, is pathogenic to humans and eels. Only a fraction of V. vulnificus strains, classified as biotype (BT) 2, is virulent for the eel, and the virulence is conferred by a common plasmid in the BT2 strains. It has been shown previously that the BT2 virulence plasmid, though itself is not transmissible, could be transferred between the BT2 strains with a frequency of about 10-2 in the presence of a conjugat...

Cheng-YuanHsieh, 謝政原

碩士 / 國立成功大學 / 微生物及免疫學研究所 / 98 / Vibrio vulnificus is a marine bacterial species pathogenic for humans and eels. There are three biotypes (BTs) of V. vulnificus, and the strains virulent for eels are classified as BT2. We have previously demonstrated that the BT2 strains possess a common plasmid that is associated with their virulence in eels. A gene, vep07, carried by the virulence plasmid, pR99, of a BT2 strain was found to be essential for bacterial virulence in eels. However, this gene alone ...

Shih-JieLin, 林士傑

碩士 / 國立成功大學 / 生物科技研究所碩博士班 / 98 / Epinephelus coioides (E. coioides, orange-spotted grouper) is an important cultivated fish in Taiwan, but various fish diseases cause many difficulties in aquaculture. How to control these diseases were the most crucial issues in the research of aquatic industry development. In fish biology, the immune system is highly related with the disease resistant ability. Due to the long development distance between fish and vertebrate animals, the fish immune system is qu...

I-Hui Chen, 陳怡惠

碩士 / 長榮大學 / 土地管理與開發研究所 / 94 / Land readjustment is one method to be used for community reconstruction. After Chi-Chi earthquake, land readjustment was also used for partial communities’ reconstruction. In Taiwan, not every community which is adapted land readjustment as reconstruction could remain reconstructing community. So this research is collected with documents, interview and questionnaire investigation method, select two post-disaster cases in Nantou County are seleced to be analyzed whic...

Po-Jui Wu, 吳柏叡

碩士 / 大葉大學 / 分子生物科技學系碩士班 / 98 / The endocrine system involved in many physiological processes such as growth, development, tissue function, immunity and metabolism, as well as reproduction. In most vertebrates, many reproductive functions including gametogenesis, sex characteristics and sex reversion were regulated through hypothalamus-pituitary-gonadal axis (HPG axis). To date, numbers of studies have demonstrated that gonadal steroids act as regulators not only in HPG axis in teleost but also p...

Huei-Ching Li, 李惠卿

碩士 / 國立臺灣海洋大學 / 生物科技研究所 / 97 /

周芷儀

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / Three experiments were conducted to investigate the effect of different dietary levels of Cornus Officinalis powder and Cornus Officinalis extract on the growth and blood sugar of adult and juvenile Nile tilapia, Oreochromis sp. In the first trial, four isoenergetic (300.68 kcal/100g) and isonitrogenous (27.88 % CP) semipurified diet supplemented with Cornus Officinalis extract levels ranging from 0 ~ 0.2 % with 0.05 % increament were evaluated. 161.91 ± 21.87 g t...

Si-Yi Wu, 吳思怡

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / This study evaluated the effect of replacing soybean meal by maize or sorghum DDGS (Distiller’s dried grains with solubles) in the diets of grass carp (Ctenopharygodon idella). Grass carp is an important cultured herbivore. In 2002, the production is about 3.6 million tonnes which shares about 15.6% of the world freshwater aquaculture production. DDGS is a by-product of the ethanol distillery industry. Its crude protein, crude fat, mineral and vitamin are 3 folds as...

Lin Yuan-Cheng, 林園程

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / The objective of this study was to investigate the vitaminB1 metabolism of hybrid tilapia (Oreochromis niloticus × O.aureus) with a modified cannulated urine collector through the comparisons between two exogenous vitaminB1 supply methods, injection and oral administration, within a 24 -hour duration. There were three replicates each running three fish at a time. Each fish received an exogenous supply of either an injection of 5ml vitamin B1 solution with a certain ...

Tzu-Yang Line, 連子揚

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / The purpose of this study was to investigate the vitamin B6 24hr metabolism in hybrid tilapia the two input methods (forced feeding and injection) with a modified cannulated urine collector in order to monitor the changes of plasma and urine vitamin B6 concentration within after the intiation of certain amount of exogruous vitamin B6 supply lithor by oral administration or by injection a 24-hour duration . There were three replicates each having 3 runs of individual...

Shan-Cheng Li, 李善晟

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / Orange-spotted grouper (Epinephelus coioides) is one of the main culture species in Taiwan. Illumination can affect fish behavior like food intake and cannibalistic activity and concomitantly, fish growth and survival. Three experiments were conducted on this regard：I. Effects of light sources on Artemia preying, growth and survival of orange-spotted grouper larva, II. Effects of light sources on feed intake, food efficiency growth, and survival of orange-spotted gr...

Jiann-Jang Lin, 林建璋

碩士 / 國立臺灣海洋大學 / 海洋法律研究所 / 97 /

Jyun-Ruei Chen, 陳君睿

碩士 / 國立臺灣海洋大學 / 海洋生物研究所 / 97 / The slickhead Alepocephalus bicolor is the dominant species in deep-sea fish fauna of Taiwan. To understand the unknown life history pattern of the fish, biological measurements as well as otolith structural and microchemistry analyses were conducted on regularly collected samples by the demersal trawl in coastal water of NE Taiwan during 2004 and 2007. Length frequency distributions indicated that the fish inhabited in 400~600 m depth and lengths of the fish, main...

陳莉臻

博士 / 國立臺灣海洋大學 / 食品科學系 / 97 /

Huang-Ming Liu, 劉皇鳴

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / The objective of this study was to evaluate the effect of dietary CoQ10 supplementation on the growth performance and CoQ10 deposition in various tissues of tilapia(O. niloticus ×O. aureus). A 6 x 2 factorial experiment with two replicates was held for 90 days. Six dietary CoQ10 levels, 0, 200, 400, 800, 1600 and 3200ppm as the first factor and two sizes of fish, 2g and 9g as the second factor respectively. Feed was fed to fish at a daily ration of 3％ body weight. R...

Chia-Wei Chang, 張家緯

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / Using cyclic voltammetry to measure the reductive potential at different oxygen concentrations, a reductive potential ranging from -0.4 to -0.5v was obtained. The results indicate that the cell density is relative to oxygen consumption, and the residual oxygen in culture medium is proven to be directly proportional to the responding current. We analyzed oxygen consumption of the SB cells infected with TGIV by cyclic voltammetry at -0.4v. When M.O.I. is 1, a continu...

Wen-Hsiao Chuang, 莊文?

博士 / 國立臺灣海洋大學 / 水產養殖學系 / 97 / Alpha-2-macroglobulin (α-2-M) is a protease inhibitor broadly present in the plasma of vertebrates and invertebrates, and is an important non-specific humoral factor in defence system of the animals. This thesis conducted the purification and characterization of the protease inhibitor, α-2-M, from grouper Epinephelus coioides. Inhibitory activities of purified α-2-M against different proteases secreted by pathogenic bacteria were performed. Rabbit antiserum to the p...

Chun-Lin Li, 李俊霖

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 96 / A study was conducted on tilapia (Oreochromis niloticus × O. aureus) and cobia (Rachycentron canadum) focusing on lipid utilization and the effect of acclimatization in juvenile fish fed high-fat can improve its use in fish diets.Two kinds of lipid level (MF: 8%, HF: 20%) and protein (MP: 30%, LP: 20%) for tilapia, and two kinds of lipid level (MF: 12%, HF: 25%) and protein (MP: 45%, LP: 30%) for cobia were tested in the study. A series of studies were conducted on ...

Yu-Hsin Chen, 陳又新

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 96 / The value of ornamental fish depends on size、appearance、color. Coloration enhancing could bring more value to ornamental fish. Fish coloration depends on more chromatophores which can produce pigment to make high density of pigment or chromatophores distribution on the skin. The coloration in ornamental fish is also regulated by the number of chromatophores, pigmentation regulatary gene, pigment accumulation. The goals of present study are to clone Mitf gene and tyr...

Guan-Min Chen, 陳冠民

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 96 / Grouper is high economic species of aquaculture in Taiwan, and disease prevention is vital issue to grouper culturing as infectious nervous necrosis virus has caused great damages to aquaculture. Innate immunity is early development than acquired immunity which character of immediately, non-specific and temperature-independent. Mx and AMPs (antimicrobial peptides) belongs to innate immunity and its antivirus and antibacterial activity has been confirmed in some spec...

Jen-Sheng Jheng, 鄭仁勝

碩士 / 國立臺灣海洋大學 / 水產養殖學系 / 96 /

Jian-Der Chou, 周建德

碩士 / 國立臺灣海洋大學 / 食品科學系 / 97 / In this study, we show the antioxidant activity of ten peptides isolated from mackerel hydrolysates and found the tetrapeptide Val-Trp-Trp-Trp which shows the significant antioxidant activity than other peptides in mackerel hydrolysates can prevent LDL oxidation induced by copper ion. Furthermore, we demonstrated Val-Trp-Trp-Trp anti-atherosclerosis bioactivity using cell culture model. Val-Trp-Trp-Trp inhibit formation of foam cell through decreasing gene expression...

Hsin Yu Hsieh, 謝欣瑜

碩士 / 國立臺灣海洋大學 / 食品科學系 / 96 / The purpose of this thesis effects of freshwater clam (Corbicula fluminea) and I-Tiao-Gung (Glycine tomentella) extracts on the antioxidant enzymes activity. The hot water extract of freshwater clam (FC-HW) has antioxidant, hepatoprotective and anticancer effects. Clam muscle protein hydrolysates inhibited angiotensin I converting enzyme. The 95% ethanol extract of I-Tiao-Gung (GTE) showed antioxidative, anti-inflammatory and anti- stress effects. Combination of FC-H...