176163
博碩士論文
Chang, Fang-Yu, 張芳瑜
碩士 / 國立臺灣海洋大學 / 生命科學暨生物科技學系 / 103 / Mxd3 (MAX dimerization protein 3) is a transcription factor which competed with MYC binding to the MAX on the E-box to prevent the transcription started. Mxd3 expression was increase by over feeding and it downregulated pparγ (peroxisome proliferator-activated receptor gamma),cebpδ(CCAAT/enhancer-binding protein Delta),cebpα,adipoq and cav1 by Mxd3 inhibition. In addition, Mxd3 target many gene associated with obesity, such as npc1l1,osbpl11. Therefore, our ...