Reddy, Venkateshwar

Several transcription factors have been shown to play a role in myelopoiesis. PU.1, an ets-family transcription factor, is required for the development of both myeloid and lymphoid lineages while the transcription factor CCAAT/enhancer binding protein family member C/EBPalpha is essential for granulocytic development. We present here the first evidence that C/EBPalpha blocks the function of PU.1. PU.1 and C/EBPalpha interact physically and co-localize in myeloid cells. As a consequence of this i...

Antretter, Maria

Die Annahme, daß station¨are Hotspots unter den Lithosph¨arenplatten der Erde existieren,
war ¨außerst wichtig f¨ur die Erforschung der Plattentektonik. Die Hypothese
ortsfester Hotspots f¨uhrt zu dem Schluß, daß Seamount Ketten geformt werden, wobei
der Vulkanismus die Lithosph¨arenplatten durchdringt w¨ahrend sich diese ¨uber Heiße
Punkte (Hotspot...

Sirim, Pinar

Die Aktivierung von T-Lymphozyten ist ein essentieller Prozeß für die Regulation der
adaptiven Immunantwort. Hierbei werden in Folge einer Antigen-Exposition über
verschiedene Oberflächenrezeptoren intrazelluläre Signaltransduktionsprozesse initiiert,
welche in einer klonalen Expansion von T-Lymphozyten sowie deren Differenzierung zu
Effektor- oder Gedächtniszellen resultieren. Die Spezifität dieser Pr...

Matzka, Jürgen

In der hier vorgestellten Arbeit wurde gezeigt, daß das weltweit beobachtete Ph¨anomen
geringer Intensit¨at der nat¨urlichen remanenten Magnetisierung von etwa 20 Ma alten
Ozeanbasalten und das dadurch verursachte Minimum bei den Amplituden der ozeanischen
Magnetfeldanomalien auf die Tieftemperaturoxidation der Titanomagnetite zu
Titanomaghemiten zur¨uckzuf¨uhren ist.
Dazu wurden magnetische und mineral...

Wiehler, Jens

Durch die genetische Fusion mit dem Grün Fluoreszierenden Protein können seit
1994 Proteine oder Genexpression in vivo visualisiert werden, ein bedeutender
Fortschritt für die Lebenswissenschaften. Die Nutzungsmöglichkeiten können z. B.
mit der gleichzeitigen Verwendung von fluoreszenzspektroskopisch unterscheidbaren
GFP-Varianten (multispektrale Detektion) erweitert werden. Eine Veränderung der
spektra...

Gloss, Annika

Eine Vielzahl von Aktin-bindenden Proteinen beeinflußt die Dynamik des Aktin-Zytoskeletts.
Im Rahmen dieser Arbeit wurden in Dictyostelium-Amöben zwei neue Proteine beschrieben:
das neuartige Zytoskelett-Protein Villidin und eine dritte Profilin-Isoform.
Ziel des ersten Teilprojekts war es charakteristische Besonderheiten der Villidin-Sequenz
detailliert zu analysieren sowie durch molekularbiologische, biochemische und
zellbiologische Ver...

Bell, Geoffrey Weszely

Bell, Geoffrey. Behavioral response of free-ranging blue crabs to episodic hypoxia. (Under the direction of David B. Eggleston)Hypoxia is increasing in frequency and magnitude in estuarine and coastal systems throughout the world. Very little is known about how periodic hypoxic intrusions into shallow, nearshore habitats influence local migration patterns and trophic dynamics of mobile species such as the blue crab, Callinectes sapidus. Studying these behavioral responses is important because hy...

Petters, Jonathan Leonard

Single scattering albedo (omega), the ratio of scattering coefficient to total extinction coefficient, at UV wavelengths is an important aerosol radiative parameter in determining surface UV irradiance. Surface measurements of total and diffuse UV irradiance in the summer and fall of 1999 at the seven narrowband wavelength channels of an UV multifilter rotating shadowband radiometer (UVMFR-SR) at Black Mountain, NC were coupled with a tropospheric ultraviolet radiative transfer model to produce ...

McAvoy, Christopher William

The aerodynamic characteristics of the wing airfoil are critical toachieving desired aircraft performance. However, even with all of theadvances in airfoil and aircraft design, there remains little guidanceon how to tailor an airfoil to suit a particular aircraft. Typically atrial-and-error approach is used to select the most-suitable airfoil.An airfoil thus selected is optimized for only a narrow range offlight conditions. Some form of geometry change is needed to adaptthe airfoil for other fli...

Carrasco, Luis Eduardo

The objectives of this research were (1) to discover associations among economic and environmental factors of highway projects considered in environmental impact statements from 1980 to 1999 produced by the North Carolina Department of Transportation, and (2) study whether this information changed through time, including whether a discernible change occurred when biodiversity regulations were introduced. Multivariate analyses tools were used for this purpose with data collected from 43 EISs. Two...

Hicks, Kristin Adair

One of the primary impediments to the implementation of bioremediation is uncertainty about success in the field. Soils and microbial populations are heterogeneous and it is difficult to extrapolate biodegradation rates from small samples to field scale. While biodegradation rates can be estimated from microcosm studies, in situ methods offer a more meaningful gauge of resident microbial activity. One method used to estimate biodegradation rates in the field is the newly developed Push-Pull tech...

Cobb, Chester Ray

Application of anaerobic swine (Sus scrofa domesticus) lagoon liquid onto cropland by irrigation is a common method of waste disposal and treatment. Currently, the application rate of swine lagoon liquid is based on the N concentration of the lagoon liqu id and the N required by the receiver crop to obtain a realistic yield. In North Carolina, only 50% of the total N in the swine lagoon liquid applied by irrigation is considered available for plant use during the first year after application. Un...

Kennedy, Alanna Marie

Ovarian atresia was examined in striped bass in order to thoroughly characterize this physiological process. If the proper hormonal and temperature cues are not received, gravid female striped bass will initiate ovarian atresia. Although domestic broodfish used in aquaculture routinely complete ovarian growth, injections of gonadotropin or gonadotropin-releasing hormone are required to induce final oocyte maturation. Those fish not treated with hormones in a timely fashion will, instead, initiat...

Barwick, Robert Dempsey

BARWICK, ROBERT DEMPSEY. Fish Populations Associated with Habitat-Modified Piers and Natural Woody Debris in Piedmont Carolina Reservoirs. (Under the direction of Thomas Kwak and Richard Noble.)A primary concern associated with reservoir residential development is the loss of littoral habitat complexity. One potential approach to compensate for this loss is to deploy artificial habitat modules under existing piers, but the benefit of this practice on developed reservoirs has not been demonstrate...

Bianchi, Alan John

In North Carolina, the southern flounder (Paralichyths lethostigma) fishery is one of the most valuable finfish fisheries in the state. A large portion of this fishery occurs during the fall (September 15 to December 15) in the southeastern area of Pamlico Sound, North Carolina, and is conducted with gillnets. The increase in the number of gillnets employed in this fishery has begun to raise concerns among fishery managers and conservationists. These concerns include the reputation that gillnets...

Lennon, Colleen Elizabeth

LENNON, COLLEEN ELIZABETH. Like a Terrible Fish. (Under the direction of Dr. John Kessel)Like a Terrible Fish is a collection of nine original short stories, exploring feminine issues from girlhood through womanhood. The collection begins with Chrysalis, the story of a ten-year-old girl who is doing her best to accept and escape from an inflexible mother, nearsightedness that now requires corrective lenses, and the first boy who has ever taken her breath away. Burn the Witches and Jungle explore...

Carvajal-Rondanelli, Patricio Armando

AbstractCARVAJAL-RONDANELLI, PATRICIO ARMANDO.Diffusion of protease inhibitors in the muscle cell(Under the direction of Dr. Tyre Lanier)Proteases often exist in fish muscle, arising from parasites, gut leaching, or merely normal physiology. Their activity may cause undesired softening of the meat during storage or slow cooking. Several food-grade inhibitors exist which can overcome this softening if properly delivered to the intracellular sites where proteases are located. Translational diffusi...

Arkinson, Heather Leigh

Gaseous ammonia has a relatively short residence time in the atmosphere, depositing quickly back to the earths surface. Excessive ammonia deposition can enhance environmental processes such as eutrophication of aquatic ecosystems. Atmospheric ammonia that does not deposit quickly combines with acidic species, such as sulfuric acid, nitric acid, and hydrochloric acid, to form ammonium aerosols. Ammonium aerosol has a longer residence time in the atmosphere and therefore travels farther distances ...

Hewitt, David Allen

Anadromous fishes often support significant commercial and recreational fisheries.Obtaining the information needed for their effective management can be problematic,however, because of the difficulties associated with sampling coastal rivers. Objectives ofthis research were to: (1) evaluate two novel methods for characterizing the spawning runsof anadromous fishes in southeastern coastal rivers, and (2) develop a method forestimating the total size of a spawning run.<p>We operated ...

Standard, Issac Daniel

The Gold Hill fault zone is a first-order structure in the Carolina Zone of the southern Appalachians that separates medium grade ductiley deformed rocks of the Charlotte terrane from low grade, mildly deformed rocks of the Carolina terrane. Based on circumstantial evidence, the Gold Hill fault zone has traditionally been viewed as a Devonian dextral shear zone. However, at the western boundary of the Carolina terrane, Late Ordovician, northeast trending, en echelon regional folds are truncated ...

duarte, natasha

Understanding how management affects long-term site productivity will help sustain forest productivity. In 1991, the USDA Forest Service installed the Long-Term Soil Productivity study in the Croatan National Forest in Craven County, NC. The study objectives were to compare indices of plant-available inorganic N from ion-exchange resin (IER) in bead and membrane form and aerobic incubations in a 8-week study, and to analyze the effects of harvest intensity and site preparation on N availability ...

Sheik Nainar, Mohamed Ashraf Ali

The goals of this study included evaluating the affects of different types of communication network delays on remote-control rover (telerover) performance, operator telepresence experiences and workload. The study also evaluated the utility of gain adaptation for communication delays on telepresence, performance and workload. Finally, the work examined the relationship between performance and subjective presence in an Internet-based teleoperation scenario utilizing a virtual reality (VR) interfa...

Straight, William Herbert

Vertebrate fossils in the lower Horseshoe Canyon Formation are remains of dinosaurs, crocodilians, champsosaurs, turtles, and fish supported during the last ~2 m.y. of the Campanian by a coastal lake-strewn wetland occupying what is now south-central Alberta, Canada. Bones accumulated on the floodplain through attritional mortality and are preserved unweathered except for surface polish, scratches, and mottling characteristic of bioturbation during rapid burial in fine-grained sediment. Fossil-b...

Yip-Hoi, Trevor Andrew

</head><body lang=EN-US style= tab-interval:.5in ><div class=Section1><p class=MsoNormal style= line-height:175% ><b style= mso-bidi-font-weight:normal >Abstract<o:p></o:p></b></p><p class=MsoBodyTextIndent style= text-align:justify;line-height:175% ><o:p> </o:p></p><p class=MsoBodyTextIndent style= t...

JOE, MIJEOM

<p><P> Ecologists and conservation biologists have had an increasing interest in landscapeecology, fragmentation and meta-population structures and dynamics for endangered or threatened species of wildlife (Nichols et al. 1992).They have realized the need for parameter estimates to use in the multi-state models;and have tried estimation of transitionprobabilities among stages using tag-return and capture-recapture models. Thesetransition probabilities are composed of ...

Varma, Ambrish Kant

<p><B>Varma, Ambrish Kant. Computer - Aided Tools for Seamless High DensityInterconnects. (Under the direction of Paul D. Franzon)</B><BR>This thesis presents the tool-set designed to demonstrate the possibility of using theCadence tools to design, verify and extract circuitry on the substrate along with theon-chip design. This circuitry could be an inter-chip connection that connects twodifferent chips or an intra-chip connection where a l...

Cancellieri, Paul Joseph

<p>Dinoflagellates represent a diverse group of both auxotrophic and heterotrophic protists. Most heterotrophic dinoflagellates are raptorial feeders that encounter prey using temporal-gradient sensing chemotaxis wherein cells move along a chemical gradient in a directed manner toward the highest concentration. Using short-term memory to determine the orientation of the gradient, dinoflagellates swim in a run-and-tumble pattern, alternating directed swimming with rapid changes in o...

Mahajan, Nikhil Ravindra

<p>The development of a distribution system simulator that can model new power electronic devices as well as new novel distribution schemes, such as DC distribution has been donehere. The simulator adopts the Electro-Magnetic Transient Programs (EMTP) platform to facilitate the simulation. Basic power electronic building blocks have been developed to extend the capabilities of the EMTP. These blocks include a rectifier module, a DC buck converter module, a 3-phase inverter module a...

Mountjoy, Daniel Neal

<p>The use of non-linear display methodologies has been successfullydemonstrated in a number of text- based and simple, graphic networkapplications; however, most studies have focused on computationalefficiency with very little attention to human perceptual limitations.While the benefits of non-linear displays are purported to be due toadditional context with no loss of required detail, reports of end-userperformance gains have been limited at best. This research entailed thedesign...

Skalski, Garrick Tyson

<p>The behavior of individuals in predator-prey interactions plays a fundamental role in population ecology and evolution. Accordingly, the development and assessment of theory that provides a conceptual framework for understanding and predicting behavior in predator-prey systems is of basic importance. This dissertation is focused on developing and assessing theory that provides a quantitative structure for predator-prey interactions.Chapter 1 provides a theoretical treatment of t...

DeCroix, David Scot

<p>Large-eddy simulation (LES) is a very useful tool in computationalfluid dynamics. The LES model allows one to solve a filtered set of theNavier-Stokes equations, thereby explicitly resolving scales of motionlarger than the discretization or grid size. Those motions smaller thanthe grid size are parameterized using a so-called subgrid scale model.<p>In this series of papers, we will use the TASS LES model, originallya cloud model, which has been modified to simulate...

Song, Yi

<p>SONG, YI. A Numerical Modeling Study of the Coupled Variability of Lake Victoria in Eastern Africa and the Regional Climate. (Under the direction of Dr. Fredrick H. M. Semazzi.). The objective of this investigation was to investigate and study the coupled atmosphere-lake climate system over the Lake Victoria basin, and determine the corresponding physical mechanisms that are involved. The primary research vehicle for the investigation is a fully coupled model of the regional cli...

Sims, Aaron Paul

<p>Mesoscale processes, dictated by surface characteristics, play adominant role in the development of the planetary boundary layer (PBL)structure and the formation of convection. The effect of mesoscale processeson the boundary layer structure also has significant implications in theunderstanding of circulation patterns and regional scale predictability. Largegeographical variability in North Carolina (NC) provides a wide variety ofweather events and climatological regimes.There a...

Zumbach, Eric Hudson

Scholars have traditionally regarded John Donnes three Hymns as independent works of devotional or meditative verse. This study proposes that Donnes Hymns are read properly as a tripartite sequence, one which addresses the poets desire for a spiritual union with Christ. Before that union may occur, Donne must tune the Instrument of his soul by submitting his fallen will to the will of Christ. The Hymns are that tuning, that labor of submission. As they unfold, the Hymns present the drama of Donn...

WANG, BINYU

Particulate matter in the atmosphere with aerodynamic diameter 2.5 micrometer or less (PM<sub>2.5</sub>) has been studied extensively due to its impact on human health, climate, and other environmental effects. PM<sub>2.5</sub>) in the southeast US as a whole and particularly in North Carolina (NC) are the focus of this research. The main body of this study includes two parts. The first part focuses on regional i.e. Southeast U.S. PM&lt...

Stanton, Wendy Marie

The occurrence of Appalachian cold air damming (CAD) is often associated with significant sensible weather impacts throughout the Carolinas and Virginia. CAD sensible weather, defined as below-normal maximum temperatures, overcast skies, fog, and reduced visibility, can often persist in the damming region for days. Furthermore, the confinement of a dome of low-level cold air along the eastern slopes of the Appalachians can create an environment ideal for freezing rain and sleet. Such potentially...

McCormick, Tracy Lynn

The radar and electrical characteristics of three linear leading convective/trailing stratiform midlatitude mesoscale convective systems (MCSs) that passed through Dallas-Fort Worth, Texas on the following dates are examined: 1) 7-8 April 2002, 2) 12-13 October 2001, and 3) 16 June 2002. Quantitative results from the April and June MCSs are presented, but data problems with the October MCS restricted partitioned analysis to qualitative results. The convective line produced ~69% and ~93% of the t...

Cetola, Jeffrey David

Two low-level convectively-induced turbulence (CIT) events east of the Appalachian Mountains are investigated utilizing observations, satellite, radar, and numerical simulations. Both events had an inordinate amount of low-level turbulence reported, but one event had more than twice as many severe or greater reports. The events were comparedto include the 72 hours leading up to the turbulence reportsand similarities and differences at the various scales from the synoptic to meso-alpha, meso-beta...

Blunden, Jessica

BLUNDEN, JESSICA. Characterization of Non-Methane Volatile Organic Compounds at Swine Facilities in Eastern North Carolina. (Under the direction of Dr. Viney P. Aneja)A total of 110 samples of volatile organic compounds (VOCs) were collected and analyzed in a field study to characterize such compounds emitted at six swine facilities in Eastern North Carolina between April 2002 and March 2003 as part of the Project OPEN (Odors, Pathogens, and Emissions of Nitrogen). Two baseline sites employed co...

Bartholomew, Nathanael

BARTHOLOMEW, NATHANAEL. Polyacrylamide For Turbidity Control in Runoff: Effects of Polyacrylamide, Soil, and Solution Properties. (Under the direction of Richard McLaughlin).Eroded soil discharged from construction sites is a major water quality issue. North Carolina regulations require that the turbidity of discharged waters from construction sites to non-trout streams or reservoirs not exceed 50 nephelometer turbidity units (NTU) and 10 NTU in trout waters. Polyacrylamide (PAM) has been demons...

Aguilar, Robert

<STYLE TYPE="text/css"><!--P {text-indent: 30pt;}--></STYLE><p>Despite the increasing importance of the red drum <i>Sciaenops ocellatus</i> recreational fishery, little is known about mortality rates of caught and released adult red drum. In this study, short-term hooking mortality rates (3-d) of adult red drum caught on 7/0 j-style hooks and 16/0 circle (tuna) hooks from the Neuse River, North Carolina...

Ji, Mikyoung Lee

Pyrococcus furiosus is an obligatory anaerobic hyperthermophilic archaeon(optimal growth temperature is 100oC ) which can be isolated from deep and shallow marine hydrothermal vent systems. Initially, due to the obligatory anaerobic nature of P.furiosus, it was thought that this organism did not possess the ability to detoxify reactiveoxygen species. Recent studies, however, have shown that P. furiosus produces theenzyme, superoxide reductase (SOR) which catalyzes the reduction of the reactive o...

Smith, Ryan Andrew

ABSTRACTSMITH, RYAN ANDREW. Harvesting Duckweed by Skimming. (Under the direction of Jiayang Cheng and John J. Classen.)Duckweed is a floating aquatic plant that has been used in a variety of water treatment applications. The plant must be harvested for the chemical removal from the wastewater to be complete. This project investigated the suitability of a harvesting system that would collect the plants by skimming them from the water surface to maintain the crop at a desirable density.The observ...

Fan, Chuanzhu

Fan, Chuanzhu. Molecular Phylogeny and Evolution of Dogwoods. (Under the direction of Dr. Jenny Qiu-Yun Xiang)Dogwoods consist of morphologically diverse plants, and taxonomic circumscription and phylogenetic relationships of dogwoods have long been controversial. My dissertation study has two major goals: 1) elucidate phylogenetic relationships in the dogwoods group using nuclear DNA sequences, and 2) investigate the sequence evolution and its morphological link of the myc-like anthocyanin regu...

Shimps, Elizabeth

Hypoxia events, or low dissolved oxygen (DO) conditions, occur frequently in North Carolina estuaries during the summer. These events may have harmful effects on important fish stocks, including spot (Leiostomus xanthurus) and Atlantic menhaden (Brevoortia tyrannus), but their consequences are not well understood. As part of a larger study examining effects of hypoxia on juvenile estuary-dependent fishes, I investigated direct mortality due to hypoxia in juvenile spot and Atlantic menhaden. The ...

Youssef, Mohamed A.

Development of management practices that reduce nitrogen (N) losses from agricultural lands has been the focus of research over many years. Development and testing of such practices is a complex task since it requires understanding of N dynamics in the soil-water-plant system, which is regulated by a large number of interacting physical, chemical, and biological processes. Nitrogen models are useful tools for developing and evaluating management practices for sustainable agriculture. The model, ...

Simmons, Karla Peavy

Clothing fit is a major cause of frustration for consumers today. The current sizing systems for women in the US are based on a study that is over 6 decades old. The greater influence of ethnic diversity along with changes in lifestyles since the 1940s is making our bodies look differently. New technology is allowing the rapid and accurate ability to determine the true shape of human bodies through 3D body scanning. No attempts have been made to study body shapes and sizes using the 3D body scan...

Medici, David A.

Medici, David A. Scale dependent movements and protection of the female blue crab, Callinectes sapidus. (Under the direction of Dr. Thomas G. Wolcott)Little is known about the migration of female crabs (Callinectes sapidus) to spawning grounds or how effectively they are protected by North Carolina spawning sanctuaries. To quantify migration, 300 mature female crabs were tagged and released the fall01, summer02, and fall02, at each of three locations: Neuse River, Pamlico River, and Albemarle So...

Wren, Patricia Ansley

Long-term in situ measurements have been made on the mid-continental shelf in Onslow Bay, NC to determine the frequency and direction of bottom sediment movement and the processes responsible for bottom sediment motion. As part of the Coastal Ocean Research and Monitoring Program (CORMP) at the University of North Carolina at Wilmington, a quadrapod frame with a downward looking Pulse-Coherent Acoustic Doppler Profiler (PC-ADP) and an upward looking Acoustic Doppler Current Profiler (ADCP) has b...

Zink, Jason Michael

The efficacy of coastal development regulations in North Carolina is dependent on accurately calculated shoreline erosion rates. North Carolinas current methodology for regulatory erosion rate calculation does not take advantage of emerging GIS, photogrammetric, and engineering technologies. Traditionally, historical shoreline positions from a database created in the 1970s have been coupled with a modern shoreline position to calculate erosion rates. The photos from which these historical shorel...