Carla Rosa Labarrère, and Paulo Mário Carvalho de Faria, and Edgar de Alencar Teixeira, and Marília Martins Melo

Massive production, such as fish growing in water recirculation system, imposes challenges to animals capable of altering their homeostatic balance, and is able to affect their physiological performance. Therefore, the levels of ions and serum enzymes can be used as indicators of fish health. This study aimed to analyze the blood biochemistry profile of hybrid surubim (P. reticulatum X P. corruscans) submitted to different stocking densities in water recirculation system, in two distinct stages ...

Marcos Tavares-Dias, and Maurício L. Martins, and Flávio R. Moraes

<abstract language="eng">The present work studied protozoan parasites of cultivated fishes (N = 433) from two feefishing farm situated in Franca, São Paulo, Brazil, during a period of April 1997 through March 1999. Specimens of piauçú Leporinus macrocephalus Garavello & Britski, 1988 (Anostomidae), pacu Piaractus mesopotamicus Holmberg, 1887 (Characidae) carp Cyprinus carpio Linnaeus, 1758 (Cyprinidae), Tillapia rendalli Boulenger, 1896 (Cichlidae), nile-tilapia Oreochromis niloticus Linnaeus, 1...

L.-A. Henry, and J. Moreno Navas, and J. M. Roberts

We investigated how interactions between hydrography, topography and species ecology influence the assembly of species and functional traits across multiple spatial scales of a cold-water coral reef seascape. In a novel approach for these ecosystems, we used a spatially resolved complex three-dimensional flow model of hydrography to help explain assembly patterns. Forward-selection of distance-based Moran's eigenvector mapping (dbMEM) variables identified two submodels of spatial scales at which...

S. B. Zongo, and F. G. Schmitt

We consider here pH and temperature fluctuations in marine waters, recorded at fixed points using high resolution automatic devices. We analyze time series coming from 4 monitoring stations located along French coast: one station is situated in the coastal area off Boulogne-sur-mer (Eastern English Channel) and 3 stations in the Bay of Seine. All these pH time series reveal large fluctuations at all scales similar to turbulent temperature fluctuations. We compare the pH and temperature time seri...

Franmir Rodrigues Brandão, and Levy de Carvalho Gomes, and Edsandra Campos Chagas

O pirarucu é um peixe nativo da bacia Amazônica com respiração aérea obrigatória. Em condições de criação, atinge até 10 kg em um ano, sendo um dos peixes com maior potencial para criação na Amazônia. O objetivo deste estudo foi avaliar as respostas de estresse em pirarucu quando submetido a práticas comuns em sistema de criação. Para isso, foram realizados três diferentes experimentos: 1) transporte; 2) adensamento; e 3) exposição à amônia. Foram analisados parâmetros do metabolismo energético ...

Katarzyna Zofia Gdowska, and Roger Książek

Background: In this paper a cyclic delivery-scheduling problem with vehicles serving fixed routes is presented. Each vehicle is assigned to one route to which some manufacturers&#39; warehouses and logistics centers belong. A&nbsp;vehicle is to be loaded at a manufacturer&#39;s warehouse, then to deliver goods to a logistics center and may be also loaded there with other goods and to transport them to the next node along the route. One logistic center belongs to several routes, so the goods deli...

Eric David Dibble, and Sidinei Magela Thomaz

We used a computerized approach to measure spatial complexity for the structural habitat provided by eight aquatic plant species collected from backwater lagoons located in the Upper Paraná River floodplain, Brazil. The plant species were: Cabomba furcata Schult. and Schult.f., Eichhornia azurea (Sw.) Kunth (stems and roots), Eichhornia crassipes (Mart.) Solms, Egeria najas Planchon, Heteranthera cf. zosterifolia, Potamogeton cf pusillus, Utricularia foliosa L., and Nymphaea amazonum Mart. and Z...

W. Lefebvre, and H. Goosse

The global sea ice-ocean model ORCA2-LIM is used to investigate the impact of the thermal and mechanical forcing associated with the Southern Annular Mode (SAM) on the Antarctic sea ice-ocean system. The model is driven by idealized forcings based on regressions between the wind stress and the air temperature at one hand and the SAM index the other hand. The wind-stress component strongly affects the overall patterns of the ocean circulation with a northward surface drift, a downwelling at about...

Kopelowicz A, and Baker RA, and Zhao C, and Brewer C, and Lawson E, and Peters-Strickland T

Alex Kopelowicz,1 Ross A Baker,2 Cathy Zhao,2 Claudette Brewer,3 Erica Lawson,3 Timothy Peters-Strickland2 1David Geffen School of Medicine, University of California, Los Angeles, CA, 2Otsuka Pharmaceutical Development and Commercialization Inc., Princeton, NJ, 3Otsuka Pharmaceutical Development and Commercialization Inc., Rockville, MD, USA Background: Medication nonadherence is common in the treatment of serious mental illness (SMI) and leads to poor outcomes. The digital medicine system (DM...

Sempere AP, and Vera-Lopez V, and Gimenez-Martinez J, and Ruiz-Beato E, and Cuervo J, and Maurino J

Angel Perez Sempere,1 Vanesa Vera-Lopez,2 Juana Gimenez-Martinez,1 Elena Ruiz-Beato,3 Jes&uacute;s Cuervo,4 Jorge Maurino5 1Department of Neurology, Hospital General Universitario de Alicante, Alicante, 2Department of Statistics, University of Salamanca, Salamanca, 3Health Economics and Outcomes Research Unit, Roche Farma SA, Madrid, 4Health Economics and Outcomes Research, Oviedo, 5Medical Department, Roche Farma SA, Madrid, Spain Purpose: Multidimensional unfolding is a multivariate method t...

Alfredo Carvalho Filho, and Carlos Eduardo Leite Ferreira

Serranus aliceae n. sp. is described from Rio de Janeiro and Espírito Santo States, southeastern Brazilian coast. The species is readily distinguished from its congeners by the following combination of characters: scales around the caudal peduncle 20 or 21; total gill rakers on first branchial arch 23-29; cheek-scales rows 5 or 6; and by the coloration of live specimens, which are reddish with a broad, conspicuous, white stripe from post-orbital region to the caudal-fin base and a white abdomen....

ORD W.

Dans le cadre du développement d'un plan national de prophylaxie sanitaire, des recherches ont été entreprises pour éprouver la sensibilité des différentes espèces de salmonidés à l'infection par le virus de la Septicémie Hémorragique Virale (S.H.V.). Le comportement du saumon chinook (Oncorhynchus tschawytscha) a été examiné et cet animal s'est révélé réfractaire à l'infection expérimentale réalisée par l'injection intrapéritonéale de 104 unités formant plage (u.f.p.) par animal d'un p...

Broyer J., and Curtet L.

Fishponds are man-made ecosystems where fish farming may strongly interfere with biodiversity. Intensified practices could be suspected to have a negative impact on animal and plant communities. We investigated the hypothesis that, in French fishponds, taxonomic richness and biomass density of macrophyte-dwelling macro-invertebrates could be influenced by fish stock density and pond fertilization. With a sample of 95 water bodies from three of the most important fishpond regions, studie...

Dvornik Joško, and Dvornik Srđan

This paper presents the simulation model for determining the intervals of preventive replacement of the system's components. The application of the Weibull distribution has been proved to be efficient in the approximation of many forms of delay, while numerical integration supported by Simpson formula and Fortran software has been applied to simulate optimum values of the preventive replacement of the components of the rotary cap burner SAACKE, type SKV 60 in the marine steam b...

MARINOV Mihai , and DOROŞENCU Alexandru, and ALEXE Vasile , and NANU Cristina, and KISS Janos Botond

In the Natura 2000 site, ROSPA 0060 Taşaul - Corbu Lakes, the nesting of Dalmatian Pelican (elecanus crispus Bruch 1832) have been confirmed in 2016. The presence of the species in the breeding season was regurarly recorded in this location since 2008. The novelty is that it is the first proved nesting of the species in Romania, except the Danube Delta Biosphere Reserve perimeter, in the last 100 years. The colony is located on the La Ostrov island on Taşaul Lake (Constanţa county). The island h...

Liliane de L. G. Souza, and Sathyabama Chellappa, and Hélio de C. B. Gurgel

A biologia reprodutiva do peixe-donzela, Stegastes fuscus Cuvier, 1830 (Perciforemes, Pomacentridae), foi estudada nos arrecifes rochosos da praia de Búzios, Nísia Floresta, Rio Grande do Norte, Brasil. Os peixes foram coletados mensalmente, medidos, pesados, dissecados, as gônadas foram removidas, pesadas e examinadas para identificação do sexo. Avaliação macroscópica dos estádios de maturação gonadal foi realizada. Um total de 549 exemplares foi capturado durante o período de outubro de 2004 a...

J. P. Cuif, and Y. Dauphin

This paper gathers a series of structural and biochemical in situ characterizations carried out to improve our knowledge of the fine scale growth patterns of fibres in coral skeletons. The resulting data show a clear correspondence between the mineral subunits of fibres and the spatial distribution of organic macromolecules. New observations using atomic force microscope confirm the close relationship between mineral and organic phases at the nanometre scale. <br /><br /> Synthesis of these data...

I. Bashmachnikov, and X. Carton

Meddies, intra-thermocline eddies of Mediterranean water, can often be detected at the sea surface as positive sea-level anomalies. Here we study the surface signature of several meddies tracked with RAFOS floats and AVISO altimetry. <br><br> While pushing its way through the water column, a meddy raises isopycnals above. As a consequence of potential vorticity conservation, negative relative vorticity is generated in the upper layer. During the initial period of meddy acceleration after meddy f...

Astuti Maryani Paramita, and Xie Rongjing, and Aziz Nicky Satyadharma

Ultra violet (UV) dechlorination was performed to eliminate residual chlorine as the byproducts of chlorination process. UV dechlorination utilizes photon energy generated by medium pressure (MP) UV lamp to produce powerful hydroxyls which in return break down chemical bond of the residual chlorine. This study was undertaken to investigate the removal of residual chlorine under a medium pressure UV radiation and evaluate the influence of UV fluence on chlorine removal efficiency based on both la...

FM. Ramos, and MLG. Araújo, and G. Prang, and RY. Fujimoto

I. Bianchini Jr., and MB. Cunha-Santino, and RS. Panhota

The kinetics of oxygen consumption related to mineralisation of 18 taxa of aquatic macrophytes (Cyperus sp, Azolla caroliniana, Echinodorus macrophyllus, Eichhornia azurea, Eichhornia crassipes, Eleocharis sp1, Eleocharis sp2, Hetereanthera multiflora, Hydrocotyle raniculoides, Ludwigia sp, Myriophyllum aquaticum, Nymphaea elegans, Oxycaryum cubense, Ricciocarpus natans, Rynchospora corymbosa, Salvinia auriculata, Typha domingensis and Utricularia foliosa) from the reservoir of Piraju Hydroelect...

Cesar Rodriguez, and Oscar Galli, and Daniela Olsson, and Javier S. Tellechea, and Walter Norbis

D. Badoud, and M. Schneider, and S. Menghetti, and B. Glaser, and M. Debbané, and S. Eliez

Abstract Background Although significant impairments in the affective and cognitive facets of social cognition have been highlighted in patients with 22q11.2 deletion syndrome (22q11DS) in previous studies, these domains have never been investigated simultaneously within the same group of participants. Furthermore, despite theoretical evidence, associations between these two processes and schizotypal symptoms or social difficulties in this population have been scarcely examined. Methods Twenty-n...

Mario Baumgart, and Emanuel Barth, and Aurora Savino, and Marco Groth, and Philipp Koch, and Andreas Petzold, and Ivan Arisi, and Matthias Platzer, and Manja Marz, and Alessandro Cellerino

Abstract Background The short-lived fish Nothobranchius furzeri is the shortest-lived vertebrate that can be cultured in captivity and was recently established as a model organism for aging research. Small non-coding RNAs, especially miRNAs, are implicated in age dependent control of gene expression. Results Here, we present a comprehensive catalogue of miRNAs and several other non-coding RNA classes (ncRNAs) for Nothobranchius furzeri. Analyzing multiple small RNA-Seq libraries, we show most of...

Pablo Lodeiro, and Thomas J. Browning, and Eric P. Achterberg, and Aurélie Guillou, and Mohammad S. El-Shahawi

Abstract Inputs of silver nanoparticles (AgNPs) to marine waters continue to increase yet mechanisms of AgNPs toxicity to marine phytoplankton are still not well resolved. This study reports a series of toxicity experiments on a representative coastal marine diatom species Chaetoceros curvisetus using the reference AgNP, NM-300K. Exposure to AgNPs resulted in photosynthetic impairment and loss of diatom biomass in proportion to the supplied AgNP dose. The underlying mechanism of toxicity was exp...

M V Botnaryuk

The questions of competitiveness raising of sea transport junction in new economy terms are considered in the article. The revision of present ways of competitiveness raising of sea port is done. The necessity of new conception from sea port to sea transport junction is exposed. Sea transport junction as complex of separate companies, which meets buyers wishers (ships owners and cargos owners) is considered. The influence of new economy on competitive strategy of sea transport junction is clarif...

D. A. Hegg, and D. S. Covert, and H. H. Jonsson, and R. K. Woods

Aircraft-based measurements of aerosol light-scattering coefficient, cloud condensation nuclei (CCN) measured directly or by proxy, and aerosol chemical composition are reported for three different years in the region of the large stratocumulus deck off the California coast. Receptor modeling is used to differentiate the contributions of the main aerosol sources to the light scattering and CCN activity. The contribution of anthropogenic sources to the two climatically important aerosol parameter...

A. M. Treguier, and J. Deshayes, and J. Le Sommer, and C. Lique, and G. Madec, and T. Penduff, and J.-M. Molines, and B. Barnier, and R. Bourdalle-Badie, and C. Talandier

The meridional transport of salt is computed in a global eddy-resolving numerical model (1/12° resolution) in order to improve our understanding of the ocean salinity budget. A methodology is proposed that allows a global analysis of the salinity balance in relation to surface water fluxes, without defining a "freshwater anomaly" based on an arbitrary reference salinity. The method consists of a decomposition of the meridional transport into (i) the transport by the time–longitude–depth mean vel...

K. J. Voss, and A. Morel, and D. Antoine

The radiance viewed from the ocean depends on the illumination and viewing geometry along with the water properties, and this variation is called the bidirectional effect. This bidirectional effect depends on the inherent optical properties of the water, including the volume scattering function, and is important when comparing data from different satellite sensors. The current model of <i>f/Q</i>, which contains the bidirectional effect, by Morel et al. (2002) depends on modeled, not measured, w...

Romuald Czerpak, and Andrzej Bajguz, and Alicja Piotrowska, and Renata Dobrogowska, and Marzena Matejczyk, and Wojciech Wiesławski

This study concerns on the influence of diamines (agmatine, putrescine) and polyamines (spermine, spermidine) upon the growth and the content of chlorophyll a and b, monosaccharides and proteins in the cells of alga Chlorella vulgaris Beijerinck (Chlorophyceae). In the experiments agmatine, putrescine, spermine and spermidine in the range of concentrations 10-6-10-3 M were used. At the concentration 10-3 M and the 1st day of cultivation, they have a toxic effect on growth of the algae. It was fo...

Liseth Pérez, and Julia Lorenschat, and Julieta Massaferro, and Christine Pailles, and Florence Sylvestre, and Werner Hollwedel, and Gerd-Oltmann Brandorff, and Mark Brenner, and Islebe Gerald, and María del Socorro Lozano, and Burkhard Scharf, and Antje Schwalb

Chironomids, diatoms and microcrustaceans that inhabit aquatic ecosystems of the Northern Neotropics are abundant and diverse. Some species are highly sensitive to changes in water chemical composition and trophic state. This study was undertaken as a first step in developing transfer functions to infer past environmental conditions in the Northern lowland Neotropics. Bioindicator species abundances were related to multiple environmental variables to exploit their use as environmental and paleoe...

Marković Goran, and Mladenović Jelena, and Cvijović Milica, and Miljković Jelena

Total protein and lipid contents were analysed in 5 samples of canned fish (sardines, Atlantic mackerel fillets, tuna in olive oil, smoked Baltic sprat and herring fillets) available on the Serbian market. Standard methods for the determination of protein (Kjeldahl method) and lipid (Soxhlet method) contents were used on drained samples. The protein content was 21.31% on average, with a range of 18.59% - 24.17%. Total lipids showed considerably large variations (5.49% - 35.20%), and averaged 18....

L. S. A. Barroco, and C. E. C. Freitas, and Á. C. Lima

Abstract The effect of catch-and-release fishing on the survival of peacock bass (Cichla spp.) was evaluated by comparing two types of artificial bait (jig and shallow-diver plugs) and two types of post-catch confinement. Two experiments were conducted during the periods January-February and October-November 2012 in the Unini River, a right-bank tributary of the Negro River. In total, 191 peacock bass were captured. Both groups of fish were subjected to experimental confinement (collective and i...

Gil Vianna Paim, and Valdson de Angelis Côrtes

Examinaram-se 594 diafragmas de roedores capturados na zona portuária de Santos tendo em vista a procura de larvas de Trichinella spiralis. Todos os diafragmas examinados estavam negativos.<br>Five hundred and ninety-four diaphragms of rodents captured in the Santos dock area were examined for Trichinella spiralis. The results of the examinations were negative.

Marcelo Ferreira Fernandes, and Roberta Pereira Miranda Fernandes, and Luciana da Silva Rodrigues

Objetivou-se neste trabalho, isolar, identificar e quantificar bactérias diazotróficas existentes nas raízes e folhas de coqueiro (híbrido PB121) cultivados na baixada litorânea de Sergipe. As populações de bactérias diazotróficas nesses órgãos foram quantificadas pela técnica do número mais provável (NMP) em meios semi-sólidos JNFb e NFb, e identificadas por meio de avaliações microscópicas, culturais e de testes bioquímicos dos sistemas API 20 - E e API 20 - NE. O conteúdo de N em meios semi-s...

Ana F. Vigário, and Simone M.T. Sabóia-Morais

The 2,4-dichlorophenoxyacetic acid, usually named 2,4-D is one of the most widely used herbicides in the world. Acute toxicity of 2,4-D herbicide was investigated through its effects on guppies (Poecilia vivipara Bloch et Schneider 1801). Fish were exposed to the herbicide at concentrations of 10, 20 and 40µl per liter of water for 24 hours to determine its effects on gills and liver epithelia. The estimated LC50 was 34.64µl of 2,4-D per liter of water. Histochemical analyses and Feulgen's react...

De Backer L, and Vos W, and Dieriks B, and Daems D, and Verhulst S, and Vinchurkar S, and Ides K, and De Backer J, and Germonpre P, and De Backer W

L De Backer&amp;sup1;, W Vos&amp;sup2;, B Dieriks&amp;sup1;, D Daems&amp;sup1;, S Verhulst&amp;sup1;, S Vinchurkar&amp;sup2;, K Ides&amp;sup1;, J De Backer&amp;sup2;, P Germonpre&amp;sup1;, W De Backer&amp;sup1;1Antwerp University Hospital, Department of Respiratory Medicine, 2FluidDa, Antwerp, BelgiumIntroduction: Noninvasive ventilation (NIV) is a well-established treatment for acute-on-chronic respiratory failure in hypercapnic COPD patients. Less is known about the effects of a long-term tre...

C. Giry, and T. Felis, and M. Kölling, and W. Wei, and G. Lohmann, and S. Scheffers

Several proxy-based and modeling studies have investigated long-term changes in Caribbean climate during the Holocene, however, very little is known on its variability on short timescales. Here we reconstruct seasonality and interannual to multidecadal variability of sea surface hydrology of the southern Caribbean Sea by applying paired coral Sr/Ca and &delta;¹⁸O measurements on fossil annually banded <i>Diploria strigosa</i> corals from Bonaire. This allows for better understanding o...

L.L. SILVA, and Q.I. GARLET, and G. KOAKOSKI, and T.A. OLIVEIRA, and L.J.G. BARCELLOS, and B. BALDISSEROTTO, and A.M.S. PEREIRA, and B.M. HEINZMANN

RESUMO:The effects of anesthesia with the essential oil of Ocimum gratissimum (EOO) in parameters of stress after handling were investigated in silver catfish (Rhamdia quelen). EOO was obtained from the aerial parts by hydrodistillation. Juveniles were anesthetized with 70 or 300 mg L-1 EOO and submitted to air exposure for 1 minute. The fishes were sampled immediately or transferred to anesthetic-free aquaria until sampling. In the first experiment, juveniles had their blood collected at 0, 1, ...

Amit eLampit, and Harry eHallock, and Chao eSuo, and Chao eSuo, and Sharon L Naismith, and Michael eValenzuela

Computerized cognitive training (CCT) is a safe and inexpensive intervention to enhance cognitive performance in the elderly. However, the neural underpinning of CCT-induced effects and the timecourse by which such neural changes occur are unknown. Here, we report on results from a pilot study of healthy older adults who underwent three 1-hour weekly sessions of either multidomain CCT program (n = 7) or an active control intervention (n = 5) over 12 weeks. Multimodal magnetic resonance imaging (...

Mónica García Solarte, and Carlos Hernán González Campo, and Guillermo Murillo Vargas

Esta investigación caracteriza el comportamiento de las pymes según la gerencia sea hombre o mujer. Para lograr el objetivo, se aplicó una encuesta estructurada a 142 gerentes de Cali. Los resultados obtenidos dan cuenta de que las pymes que son dirigidas por mujeres son pocas, de mayor tamaño, tienen menor participación femenina dentro de sus empleados pero mayor participación dentro de las juntas directivas, no pertenecen ampliamente a organizaciones de carácter familiar, tienen mayores socios...

Mamdouh M. El-Hattab

Land cover changes considered as one of the important global phenomena exerting perhaps one of the most significant effects on the environment than any other factor. It is, therefore, vital that accurate data on land cover changes are made available to facilitate the understanding of the link between land cover changes and environmental changes to allow planners to make effective decisions. In this paper, the post classification approach was used to detect and assess land cover changes of one of...

Jesse L. Clark, and Eddy R. Segura, and Catherine E. Oldenburg, and Jessica Rios, and Silvia M. Montano, and Amaya Perez-Brumer, and Manuel Villaran, and Jorge Sanchez, and Thomas J. Coates, and Javier R. Lama

Abstract Background Expedited Partner Therapy (EPT) has been shown to improve treatment outcomes among heterosexual partners of individuals with curable sexually transmitted infections (STIs). Although the use of EPT with men who have sex with men (MSM) has been debated, due to the potential for missed opportunities to diagnose unidentified cases of HIV and syphilis infection in symptomatic partners, increases in partner notification (PN) resulting from use of EPT may promote testing and treatme...

Andrea Nuzzo, and Andrea Negroni, and Giulio Zanaroli, and Fabio Fava

Abstract Background Microbial reductive dechlorination of polychlorinated biphenyls (PCBs) plays a major role in detoxifying anoxic contaminated freshwater and marine sediments from PCBs. Known members of the phylum Chloroflexi are typically responsible for this activity in freshwater sediments, whereas less is known about the microorganisms responsible for this activity in marine sediments. PCB-respiring activities were detected in PCB-impacted marine sediments of the Venice Lagoon. The aim of ...

Jean-Pierre Chupin, and Andrés Ávila-Gómez, and Diana Carolina Ruiz-Robayo

<p><strong>Resumen</strong><br />A partir de dos interrogantes fundamentales en torno al significado de la investigación doctoral en arquitectura, y en torno también a sus objetivos, métodos y fronteras disciplinares, se expone un modelo de orientación pedagógica para los productos doctorales concebido como una “brújula de navegación para teorías y tesis”: su utilización ofrece al menos ocho perspectivas para orientar y clasificar las tesis en arquitectura con base en la diferenciación de los ti...

James S. Evans, and Patrick M. Erwin, and Noa Shenkar, and Susanna López-Legentil

Abstract Many ascidian species have experienced worldwide introductions, exhibiting remarkable success in crossing geographic borders and adapting to local environmental conditions. To investigate the potential role of microbial symbionts in these introductions, we examined the microbial communities of three ascidian species common in North Carolina harbors. Replicate samples of the globally introduced species Distaplia bermudensis, Polyandrocarpa anguinea, and P. zorritensis (n = 5), and ambien...

Akram Khan, and Cody Benthin, and Brian Zeno, and Timothy E. Albertson, and John Boyd, and Jason D. Christie, and Richard Hall, and Germain Poirier, and Juan J. Ronco, and Mark Tidswell, and Kelly Hardes, and William M. Powley, and Tracey J. Wright, and Sarah K. Siederer, and David A. Fairman, and David A. Lipson, and Andrew I. Bayliffe, and Aili L. Lazaar

Abstract Background Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme 2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We postulated that repleting ACE2 using GSK2586881, a recombinant form of human angiotensin-converting enzyme 2 (rhACE2), could attenuate acute lung injury. Methods We conducted a two-part phase II trial comprising an open-label intrapatient dose escalation and a randomized, double-blind, placebo-controlled...

Marco Otávio Dias Pivari, and Pablo Hendrigo Alves de Melo, and Filipe Soares Souza, and João Renato Stehmann, and Edson Gomes de Moura Júnior, and Suzana Neves Moreira, and Vali Joana Pott, and Arnildo Pott, and Aline Lopes, and Maria Cecilia Chiara Moço, and Lukiel dos Santos Oliveira, and Alba Lucia de Almeida Lins, and Rafael Arruda, and Isa Lucia de Morais, and Gustavo Santos Silva, and Régis Moreira Ferreira

ABSTRACT Initiatives directed at managing information on aquatic plants can support different areas of scientific research, educational practices and political decisions for sustainable management and protection of wetlands and natural resources, as well as reveal knowledge gaps regarding aquatic plants and wetlands. Furthermore, such initiatives can contribute directly to consolidating wetland classification systems in Brazil. The objectives of this work are to present and explore the use of a ...

Katsuaki Yokoyama, and Shigemasa Tani, and Rei Matsuo, and Naoya Matsumoto

Abstract Background Lecithin-cholesterol acyltransferase (LCAT) is believed to be involved in reverse cholesterol transport, which is known to play a key role in suppression of atherosclerosis. However, recent investigations have demonstrated that higher LCAT activity, measured in terms of the serum cholesterol esterification rate by an endogenous substrate method, is associated with increased formation of triglyceride (TG)-rich lipoproteins (TRLs), leading to a decrease in the low-density lipop...

Niranzena Panneer Selvam, and Jayachandran Sadaksharam, and Ganesan Singaravelu, and Rajasekaran Ramu

Aim of the Study: Oral leukoplakia (OL) is the most common potentially malignant disorder that may transform into oral carcinoma. By treating leukoplakia in its incipient stage, the risk of occurrence of oral carcinoma can be prevented. In this aspect, photodynamic therapy (PDT) can serve as a useful treatment modality. The aim of the study is to treat patients with OL using PDT in which 5-aminolevulinic acid (ALA) is used as a photosensitizer. Materials and Methods: Five patients with OL were ...