M. Bérubé, and V. Deslauriers, and S. Leduc, and V. Turcotte, and S. Dupuis, and I. Roy, and S. Clairoux, and S. Panic, and M. Nolet

Abstract Background Opioid use disorder (OUD) and deaths related to the chronic use of opioids have increased significantly over the last two decades. Chronic consumption of opioids has been documented in many patients with traumatic injuries. Preliminary research findings have shown that interventions using cognitive-behavioral strategies were a promising adjunct in decreasing the burden associated with opioid consumption. Accordingly, the Tapering Opioids Prescription Program in Trauma (TOPP-T...

Scott Hamilton, and Kevin McLean, and Sean J. Monaghan, and Carol McNair, and Neil F. Inglis, and Hazel McDonald, and Sandra Adams, and Randolph Richards, and William Roy, and Patrick Smith, and James Bron, and Alasdair J. Nisbet, and David Knox

Abstract Background The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the host immune system. Other ectoparasitic invertebrates produce compounds in their saliva, excretions and/or secretions which modulate the host immune responses allowing them to remain on or in the host during development. Similarly, compoun...

Amr Kandeel, and Danielle L. Palms, and Salma Afifi, and Yasser Kandeel, and Ahmed Etman, and Lauri A. Hicks, and Maha Talaat

Abstract Background Antibiotic overuse is the most important modifiable factor contributing to antibiotic resistance. We conducted an educational campaign in Minya, Egypt targeting prescribers and the public through communications focused on appropriate antibiotic use for acute respiratory infections (ARIs). Methods The entire population of Minya was targeted by the campaign. Physicians and pharmacists were invited to participate in the pre-intervention assessments. Acute care hospitals and a sa...

Oscar L. Olvera Astivia, and Anne Gadermann, and Martin Guhn

Abstract Background Despite its popularity, issues concerning the estimation of power in multilevel logistic regression models are prevalent because of the complexity involved in its calculation (i.e., computer-simulation-based approaches). These issues are further compounded by the fact that the distribution of the predictors can play a role in the power to estimate these effects. To address both matters, we present a sample of cases documenting the influence that predictor distribution have on...

Manoj Kumar Das, and M Rajesh Kumar Rao, and A K Kulsreshtha

Background & objectives: Mosquitoes are responsible for transmitting several diseases, including malaria, dengue, chikungunya, filariasis, and yellow fever, etc. Release of larvivorous fishes is one of the cheapest method of vector management approach, with long suppression of mosquito population. The present study identifies the native larvivorous fishes and evaluates their potential larvivoracity for biological control of mosquito larvae in an endemic malarious region. Methods: During the yea...

Gerdeaux D., and Dufour E.

Stable isotope analysis (SIA) of fish otoliths shows great potential for exploring the ecology of fish, but this method has not been applied to the study of lacustrine fish communities. Both sequential and whole-otolith SIAs were performed on six fish species of Lake Annecy and their results compared to muscle SIA. The first purpose of these investigations was to test the use of δ18Ooto values for reconstructing fish thermal history and delimitin...

Sourabh Aggarwal, and Jesna Mathew, and Harkirat Singh, and Vishal Sharma

Objective: To analyze the attitude and perception of junior resident doctors' regarding antibiotic resistance and prescribing. Methods: This cross-sectional study was conducted in two tertiary care centres in the New Delhi during the months of May-June 2012. An email based questionnaire was emailed to all the junior residents (JRs) working in the clinical setting and all the responses obtained within 2 months were included in the study. Statistical analysis was done using SPSS v.17. Results: Thi...

Vesa Korhonen, and Hannu Räty, and Eija Kärnä

High support need and minimally verbal individuals with autism have received less attention in research in comparison to so-called higher functioning individuals with autism. As computers motivate individuals with autism, a game with a positive user experience was altered into a level 1 perspective-taking task in which advancement was contingent on eye contact. A case-controls design was used to see whether participants had impaired perspective taking and would they benefit from additional cues....

Alfredo Pérez-Morales, and Christine J. Band-Schmidt, and Sergio F. Martínez-Díaz

In the shrimp culture, larval stages have high mortality rates, particularly in the zoea stage, this because to the star of phytoplankton feeding and an inadequate microalga species and cell density used in commercial hatcheries. Several microalgae species are used as food in shrimp larviculture, and the most common are Chaetoceros calcitrans and Tetraselmis suecica. Therefore, in this study, we quantied changes in the mortality rates of zoea larvae of L. vannamei fed either C. calcitrans o...

Nuengruetai Yoknoi, and Jes Kettratad, and Nittharatana Paphavasit, and Prasert Tongnunui

This study aimed to describe development patterns and define length at juvenile of two co-occurring terapontid fishes. Terapon jarbua (n=366, 1.49-48.24 mm) and Pelates quadrilineatus (n=314, 1.64-54.13 mm) were collected from coastal area, Trang Province, Thailand. Specimens were divided into five developmental stages: preflexion larvae, flexion larvae, postflexion larvae, transforming larvae, and juvenile by study of morphometric character, meristic character and pigmentation pattern. The ...

Nilgün Kaba, and Emre Çağlak

İsmet Balık, and Hıdır Çubuk

Ana Paula Frederico Rodrigues Loureiro Bracarense, and Carmino Hayashi, and Elisabete Yurie Sataque Ono, and Maria Angela do Santos, and Elisabete Hiromi Hashimoto, and Elisa Yoko Hirooka

With intention to supply the demand and progress of aquaculture, the industrial sector invested in the production of feed, whose formulation depends on grains susceptible for mycotoxigenic fungi. The objective of this work was to evaluate the chemical composition (nutricional quality) associated with the risk of mycotoxin contamination (aflatoxin and fumonisin) in 42 feed samples, belonging to five commercial industries, and used in fishing activity of the Region of Londrina-PR. The analysis of ...

R. J. G. Leakey, and F. C. Hawthorne, and D. Barber, and N. Halden, and K. Lennert, and M. Cooper, and R. N. Glud, and S. Rysgaard

A major issue of Arctic marine science is to understand whether the Arctic Ocean is, or will be, a source or sink for air–sea CO₂ exchange. This has been complicated by the recent discoveries of ikaite (a polymorph of CaCO₃·6H₂O) in Arctic and Antarctic sea ice, which indicate that multiple chemical transformations occur in sea ice with a possible effect on CO₂ and pH conditions in surface waters. Here, we report on biogeochemical conditions, microscop...

Luiz Antonio Fonseca de Godoy, and Ronaldo Aloise Pilli

An efficient synthesis of the marine metabolite 3-bromoverongiaquinol (1) and the first total synthesis of 5-monobromocavernicolin (2), both isolated from the marine sponge Aplysina cavernicola, have been described based on the 1,2 addition of the lithium enolate of N,O-bistrimethylsilylacetamide (BSA, 4) to 1,4-benzoquinone (3). Bromination and purification of the crude product on silica gel chromatography provided 3-bromoverongiaquinol (1) in 50% overall yield. Under alkaline conditions, the c...

G.L. Volpato, and A.C. Luchiari, and C.R.A. Duarte, and R.E. Barreto, and G.C. Ramanzini

We investigated the association of eye color with the dominant-subordinate relationship in the fish Nile tilapia, Oreochromis niloticus. Eye color pattern was also examined in relation to the intensity of attacks. We paired 20 size-matched fish (intruder: 73.69 ± 11.49 g; resident: 75.42 ± 8.83 g) and evaluated eye color and fights. These fish were isolated in individual aquaria for 10 days and then their eye color was measured 5 min before pairing (basal values). Twenty minutes after pairing, e...

Kayo Masuko, and Minako Murata, and Naoya Suematsu, and Kazuki Okamoto, and et al.

Kayo Masuko1, Minako Murata2, Naoya Suematsu1, Kazuki Okamoto1, Kazuo Yudoh2, Hiroyuki Shimizu3, Moroe Beppu3, Hiroshi Nakamura4, Tomohiro Kato11Department of Biochemistry; 2Department of Frontier Medicine, Institute of Medical Science; 3Department of Orthopedic Surgery, St. Marianna University School of Medicine, Kawasaki-shi, Kanagawa, Japan; 4Department of Joint Disease and Rheumatism, Nippon Medical School, Bunkyo-ku, Tokyo, JapanAbstract: Prostaglandin E2 (PGE2) is expressed in articular jo...

Jaime Copia, and Hernán Gaete, and Gustavo Zúñiga, and María Hidalgo, and Enrique Cabrera

Las algas marinas son una fuente importante de compuestos antioxidantes (fenoles y polifenoles), generados como mecanismos de defensa frente a factores de estrés (radiación UV, temperatura, herbívora). El objetivo de este trabajo es evaluar la estrategia de adaptación al efecto de la radiación ultravioleta B (RUV-B, 280-315 nm) en la microalga marina Chlorella sp. mediante la producción de polifenoles y capacidad antioxidante total. Se expusieron cultivos de Chlorella sp. fueron expuestos a radi...

Wladimir C. Paradas, and Gilberto M. Amado Filho

Because of its high toxicity, TBT (trybutiltin) was banned since 2003, which resulted in a greater re-use of Cu as based-biocide in antifouling paints (AFP). The aim of this work is to determine if metals form of AFP are transferred to benthic organisms from Guanabara Bay (GB) (Rio de Janeiro, Brazil). Metal concentrations were measured in two main fouling algae species Ulva flexuosa and U. fasciata and one isopod species, Sphaeroma serratum, in two GB marinas areas from sites with artificial su...

Yuru Zhang, and Chaobin Qin, and Liping Yang, and Ronghua Lu, and Xiaoyan Zhao, and Guoxing Nie

Abstract Background Glucose plays a key role as an energy source in most mammals, but its importance in fish appears to be limited that so far seemed to belong to diabetic humans only. Several laboratories worldwide have made important efforts in order to better understand this strange phenotype observed in fish. However, the mechanism of carbohydrate/glucose metabolism is astonishingly complex. Why basal glycaemia is different between fish and mammals and how carbohydrate metabolism is differen...

Federica Costantini, and Filippo Ferrario, and Marco Abbiati

Abstract Conservation of coastal habitats is a global issue, yet biogenic reefs in temperate regions have received very little attention. They have a broad geographic distribution and are a key habitat in marine ecosystems impacted by human activities. In the Mediterranean Sea coralligenous reefs are biodiversity hot spots and are classified as sensitive habitats deserving conservation. Genetic diversity and structure influence demographic, ecological and evolutionary processes in populations an...

Jonathan Alejandro Vera-Caripe, and Carlos Federico Lira Gómez, and Gabriela Carias Tucker, and Aisur Ignacio Agudo-Padrón

Abstract During exploratory trips conducted between August and December 2016, six shrimps, found in association with the crinoid Nemaster grandis A.H. Clark, 1909, ere collected in Chichiriviche de la Costa, Vargas State (Venezuela). A photographic record of the crinoids and the shrimps was conducted in situ. Shrimps were preserved in ethyl alcohol 90% and carried to the Laboratorio de Carcinología de la Universidad de Oriente, Núcleo Nueva Esparta. Once in the laboratory, the shrimps were taxon...

Farahnaz Fatemi Naini, and Alireza Vaez Shooshtari, and Bahareh Ebrahimi, and Razieh Molaei

Objective : Pseudocatalase/superoxide dismutase (PSD) is a topical gel considered having therapeutic effects in vitiligo. This study was designed to evaluate the efficacy of this combination in vitiligo. Methods : This was a pilot randomized, double-blind, placebo-controlled trial on 46 symmetrical vitiligo lesions of limbs in 23 patients referring to dermatology clinics, Isfahan, Iran in 2010. Patients were received this formula or placebo gels for the right and left lesions. Lesion area and d...

Angelica R. Soares, and Heitor M. Duarte, and Luzineide W. Tinnoco, and Renato C. Pereira, and Valéria L. Teixeira

Abstract Intraspecific variation on meroditerpenoids production by the brown marine alga Stypopodium zonale at four different populations along the Brazilian coast was analyzed using Principal Component Analysis over high-performance liquid chromatography profiles from algae extracts. The ordination of the samples by the similarities of their chromatographic traits showed the existence of three chemotypes: (i) the populations Búzios and Abrolhos which were characterized by the presence of atomar...

Erika M. Stein, and Daniel X. Andreguetti, and Cleidiane S. Rocha, and Mutue T. Fujii, and Mauricio S. Baptista, and Pio Colepicolo, and Guilherme L. Indig

The development of new anti-cancer drugs of algal origin represents one of the least explored frontiers in medicinal chemistry. In this regard, the diversity of micro- and macroalgae found in Brazilian coastal waters can be viewed as a largely untapped natural resource. In this report, we describe a comparative study on the cytotoxic properties of extracts obtained from the Laurencia complex: Laurencia aldingensis, L. catarinensis, L. dendroidea, L. intricata, L. translucida, L. sp, and Palisada...

Louisa M. A. Sousa, and Rubens L. Monte Neto, and Dionezine F. Navarro Schmidt, and Márcia R. Oliveira

Allamanda (Apocynaceae) is a genus of climbing shrubs known for producing compounds with a range of biological activities. Previous works have shown the anti-proliferative effect of the ethanolic extract of Allamanda schottii on leukemic cells. The present work was conducted to evaluate the effects of dichloromethane fraction, obtained from Allamanda schottii, on sea urchin Echinometra lucunter eggs, as a multicellular model for evaluating anti-tumor activity. Our results show an inhibition of s...

Flavo E. S. de Sousa, and Euriel A. Moura, and Eliane Marinho-Soriano

This study was designed to select potential areas for cultivation of the seaweed Gracilaria birdiae Plastino & E.C. Oliveira (Gracilariales, Rhodophyta) on the coast of Rio Grande do Norte state, Brazil. The Geographic Information System (GIS) and multi-criteria evaluation (MCE) were used to identify the most suitable areas. The Analytical Hierarchical Process (AHP) was applied to establish MCE weights, thereby generating viable areas for species cultivation. From a total of 3316.82 ha, around 5...

Trisha Towanda, and Erik V. Thuesen

Summary Some photosynthetic organisms benefit from elevated levels of carbon dioxide, but studies on the effects of elevated PCO2 on the algal symbionts of animals are very few. This study investigated the impact of hypercapnia on a photosynthetic symbiosis between the anemone Anthopleura elegantissima and its zooxanthella Symbiodinium muscatinei. Anemones were maintained in the laboratory for 1 week at 37 Pa PCO2 and pH 8.1. Clonal pairs were then divided into two groups and maintained for 6 we...

Patrick Rabe, and Tim A. Klapschinski, and Nelson L. Brock, and Christian A. Citron, and Paul D’Alvise, and Lone Gram, and Jeroen S. Dickschat

Tropodithietic acid (TDA) is a structurally unique sulfur-containing antibiotic from the Roseobacter clade bacterium Phaeobacter inhibens DSM 17395 and a few other related species. We have synthesised several structural analogues of TDA and used them in bioactivity tests against Staphylococcus aureus and Vibrio anguillarum for a structure–activity relationship (SAR) study, revealing that the sulfur-free analogue of TDA, tropone-2-carboxylic acid, has an antibiotic activity that is even stronger ...

Tingting Li, and Likun Ren, and Dangfeng Wang, and Minjie Song, and Qiuying Li, and Jianrong Li

Background Gout is the second most common metabolic disease affecting human health. The disease of gout is closely related to the level of uric acid, which is the end-product of human purine metabolism. Moreover, food is the main way of external ingestion of purine. Method A simple and time-saving method was developed to extract purines like adenine, hypoxanthine, guanine, and xanthine from marine fish by single factor design combined with Box–Behnken. The contents of these purines in the edible...

Ester Vieira Noleto, and Marcus Vinícius Moreira Barbosa, and Fernando Mayer Pelicice

Abstract Aim The present study investigated the diversity of aquatic macrophytes in the littoral zone of Lajeado Reservoir, Tocantins River. We characterized spatial variations in species richness, composition and abundance along depth gradients. Methods Macrophyte sampling occurred at the end of the dry season (September and October 2014) in four sites of the reservoir. We established transects perpendicular to the shoreline, each 25 m long, divided in 3 sections (plots of 5 x 5 m). Result...

M. Afraei1; F. Parafkandeh2; A. Janbaz1

As part of the identification and distribution mapping of Clupeid fish in southern Caspian Sea, we studied abundance and species diversity of the fish in Mazandaran and Golestan Coastal waters during August-April 1999 to 2001. In the 336 specimens studied, four species were identified including Alosa braschnikowi, Alosa caspia, Alosa saposchnikowi and Alosa kessleri. The most abundant species was Alosa braschnikowii comprising 84.4% of the individuals and Alosa kessleri was the least abundant co...

Poursina Narges, and Vatanara Alireza, and Rouini Mohammad Reza, and Gilani Kambiz, and Najafabadi Abdolhossein Rouholamini

Spray freeze drying was developed to produce dry powders suitable for applications such as inhalation delivery. In the current study, the spray freeze drying technique was employed to produce inhalable salmon calcitonin microparticles. Effects of the carrier type, concentration of hydroxyl propyl-β-cyclodextrin and the presence of Tween 80 on the chemical and structural stability, as well as on the aerosol performance of the particles were investigated. The results indicated that hydroxyl propyl...

V. V. Kanivets

The information on methodical guide for radiation monitoring of river and sea water that was prepared for publishing is presented. The guide is developed for the decision of tasks, which are assigned by the legislation on the Hydrometeorological Service of Ukraine in the field of water radiation monitoring. The short characteristic of the main parts of the guide concerning the sampling, primary processing and preparation for radionuclide analysis of water, suspended sediments, bottom deposits a...

Georgia C. Richards, and Lesley J. Lluka, and Maree T. Smith, and Catherine Haslam, and Brendan Moore, and James O'Callaghan, and Jenny Strong

Abstract. Introduction:. Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of the potential influence of opioid analgesics. Objectives:. This cross-sectional pilot study aimed to explore whether patients with CLBP receiving long-term opioid analgesics differed from patients not taking opioids on measures of cognitive performance and plasma cytokine concentrations. Methods:. Patients with CL...

Ronaldo Bastos Francini, and Marcelo Duarte, and Olaf Hermann Hendrik Mielke, and Astrid Caldas, and André Victor Lucci Freitas

Butterflies (Lepidoptera, Papilionoidea and Hesperioidea) of the "Baixada Santista" region, coastal São Paulo, southeastern Brazil. A list with 538 species of butterflies recorded in the Baixada Santista, São Paulo ( SE Brazil) is presented. Standard sampling protocols (i.e. with entomological nets) were followed. Baited traps were installed for fruit feeding species. Data from the literature and entomological collections were also considered in the total estimated species richness. The species ...

Voicu Răzvan, and Bănăduc Doru, and Baumgartner Lee Jason, and Voicu Liliana, and Curtean-Bănăduc Angela

We propose a technical solution for fish movement based on the flow of water over a spill threshold. Such barriers are common in the Danube system. The proposed system has a range of operating components which are easily detachable from the spill threshold, are resistant to corrosion and will not harm the fish. In fact, if designed to complement swimming abilities of target fish, it should provide adequate passage for both adults and juveniles. If implemented correctly, the design may offer a so...

Hassan Jafari, and Nasser Saeidi, and Mohammad Karim Karimi

One of the important issues in port services is to evaluate the performance of the services. Without evaluating port services and their related components, these services cannot be considered desirable and its quality cannot be enhanced. However, the evaluation and the quality assurance of port services should be accomplished based on a scientific framework and a coherent framework to have desirable results. The importance-performance analysis model is an appropriate framework where each compone...

G. Mongelli, and S. Monni, and G. Oggiano, and M. Paternoster, and R. Sinisi

Throughout the Mediterranean, salinization threatens water quality, especially in coastal areas. This salinization is the result of concomitant processes related to both seawater intrusion and water–rock interaction, which in some cases are virtually indistinguishable. In the Nurra region of northwestern Sardinia, recent salinization related to marine water intrusion has been caused by aquifer exploitation. However, the geology of this region records a long history from the Palaeozoic to the Qua...

A. Filonov, and V. Novotryasov

This paper studies the internal wave band of temperature fluctuation spectra in the coastal zone of Pacific ocean. It is observed that on the central Mexican Pacific Shelf in the high-frequency band of temperature spectra the spectral exponent tends to ~&amp;omega;^-1 at the time of spring tide and &amp;omega;^-2 at the time of neap tide. On the western shelf of the Japan/East Sea, in the &amp;Omega;<<&amp;omega;<< N_* range, where N_* is the representativ...

Babić Olivera B., and Simeunović Jelica B., and Škrbić Nataša Z., and Kovač Dajana J., and Svirčev Zorica B.

Cyanobacteria, as highly adaptable microorganisms, are characterized by an ability to survive in different environmental conditions, in which a significant role belongs to their enzymes. Phosphatases are enzymes produced by algae in relatively large quantities in response to a low orthophosphate concentration and their activity is significantly correlated with their primary production. The activity of these enzymes was investigated in 11 cyanobacterial strains in order to deter...

Jorge Galindo-Villegas, and E Sosa-Lima

Since 1997, Poeciliopsis infans Woolman 1894 has been recognized as a new inhabitant of Lake Patzcuaro, Michoacan in Central Mexico. Between February 1997 and October 1998, nine fish samples were collected at Lake Patzcuaro. Morphometric and meristic counts were conducted on a random selection of 40 organisms of both sexes of Poeciliopsis infans. Males of these viviparous fish posses a modified anal fin called gonopodium. The characteristic hemal spine on the 18,h caudal vertebra for this specie...

Gislaine Aparecida Vitoreli, and Luiz Cesar R Carpinetti, and Mateus Cecílio Gerolamo, and Juliano Endrigo Sordan, and Carlos Henrique Bertucci Lima

Este artigo apresenta e discute a estruturação de um programa de qualificação para pequenas e médias empresas em gestão de qualidade, segurança e saúde ocupacional. O programa de qualificação proposto inclui a estruturação de um modelo de sistema de gestão integrado bem como a estruturação dos processos de implementação e auditoria deste sistema. O método de pesquisa-ação foi adotado para a condução da aplicação piloto desta proposta que foi realizada no aglomerado metal-mecânico de Sertãozinho,...

Edgardo E. Díaz-Ferguson, and Gregory R. Moyer

Genetic material (short DNA fragments) left behind by species in nonliving components of the environment (e.g. soil, sediment, or water) is defined as environmental DNA (eDNA). This DNA has been previously described as particulate DNA and has been used to detect and describe microbial communities in marine sediments since the mid-1980’s and phytoplankton communities in the water column since the early-1990’s. More recently, eDNA has been used to monitor invasive or endangered vertebrate and inve...

Neumárcio Vilanova da Costa, and Dagoberto Martins, and Sidnei Roberto de Marchi

The continuous inputs from agriculture areas and human or industrial sewer have been provided a widely demographic explosion of tropical tanner-grass and para grasss plants in the rivers and water reservoirs of Brazil. Considering the importance of these noxious weeds there is a vast necessity of basic studies on aspects related to reproduction, growing, development, nutritional requirements, responses to control systems and others. In most studies, leaf area knowledge is crucial and it is one o...

W.F. Albuquerque, and A. Macrae, and O.V. Sousa, and G.H.F. Vieira, and R.H.S.F. Vieira

The aim of this study was to investigate the presence of antibiotic resistant Staphylococcus aureus strains in fish stalls and in hands and nasal and oral cavities of fish handlers of the Mucuripe Fish Market, Fortaleza, Ceará, Brazil. All S. aureus isolates were resistant to Ampicillin and 44 % were multi-drug resistant.<br>O objetivo da pesquisa foi investigar a presença de Staphylococcus aureus resistente a antibióticos nos boxes de venda de peixe e nas mãos e cavidades nasal e oral de manipu...

Pedro Abel Hernández-García, and Germán David Mendoza-Martínez, and Nallely Sánchez, and José Antonio Martínez-García, and Fernando Xicotencatl Plata-Pérez, and Alejandro Lara-Bueno, and Silene Mariella Ferraro

ABSTRACT The objective of this study was to evaluate the effects of four levels of fish oil on lamb performance, carcass yield, ruminal fermentation, and leptin gene expression in perirenal fat. Thirty-two lambs (24.10±2.15 kg, Katahdin × Pelibuey) were used in a completely randomized experimental design. The lambs were assigned to one of four dietary treatments (n = 8 lambs/treatment), expressed as g/kg DM basis: 0 fish oil and 300 corn; 10 fish oil and 250 corn; 20 fish oil and 205 corn; and 3...

P Mansouri, and S Mirafzal, and P Najafizadeh, and Z Safaei-Naraghi, and M H Salehi-Surmaghi, and F Hashemian

Context: Psoriasis is an inflammatory disorder, formed by inappropriate interaction of T lymphocytes with keratinocytes, and consequent eruption of immune responses. High concentrations of tumor necrosis factor-alpha (TNFα) are found in the skin lesions and plasma of patients with psoriasis. Hypericum perforatum, a phytomedicine that has both anti-inflammatory and antiproliferative properties, has been recently reported to be clinically helpful for improvement of psoriatic lesions. Aims: The aim...

Åse Bergheim, and Vibeke Graver

Questions: At our hospital, is it possible to recruit to a pilot study ten patients with subacute cerebral stroke? And do they improve differently on motor function receiving modified Constraint Induced Movement Therapy (mCIMT) versus traditional physiotherapy (TP)? Design: Randomized controlled pilot trial with follow up at three end six months after debut of symptoms. Material and Methods: Patients in subacute-phase after cerebral stroke, i.e. 14 - 21 days after symptom debut, were referre...