187147
博碩士論文
Han-Hsing Tsou, 鄒瀚興
博士 / 國立陽明大學 / 環境與職業衛生研究所 / 107 / Acrolein, a highly reactive unsaturated aldehyde and respiratory irritant, is formed during combustion (e.g., cigarette smoke, exhaust gas), high-temperature cooking of foods, and in vivo as a by product of oxidative stress and polyamine metabolism. 3-Hydroxypropyl mercapturic acid (3-HPMA), the main metabolite of acrolein in urine, is formed by glutathione (GSH) conjugation following the reduction and normal metabolic processing to a mercapturic acid.
The study ...